PMID: 6986896Jan 1, 1980Paper

Intranasal flunisolide, placebo and beclomethasone dipropionate in perennial rhinitis.

British Journal of Diseases of the Chest
M K McAllenC Engler

Abstract

Flunisolide nasal spray has been compared with placebo and with beclomethasone dipropionate in the treatment of perennial rhinitis. A double-blind, cross-over study in 26 patients comparing intranasal flunisolide (total dose 300 microgram/day) with placebo showed superiority of the active preparation in the relief of sneezing, stuffiness and runny nose. Physicians and patients significantly preferred the active spray. Side-effects on both sprays were mainly confined to transient nasal irritation. Plasma cortisol levels did not change significantly during the trial. A single-blind, cross-over study in 34 patients comparing flunisolide and beclomethasone dipropionate showed relief of sneezing, stuffiness, runny nose and nose-blowing with both medications. There were no differences between the effects of the two preparations. Physicians and patients favoured the drugs equally. Side-effects were minor.

References


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Citations

Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Sujani KakumanuTimothy Craig
Sep 10, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H MilgromC C Wood
Jan 1, 1984·Current Medical Research and Opinion·A F Langrick
Oct 1, 1982·Clinical Otolaryngology and Allied Sciences·N Mygind
Mar 1, 1987·Acta Oto-laryngologica·N YagiR Ichikawa
Nov 5, 2019·The Cochrane Database of Systematic Reviews·Christine SegboerWytske Fokkens
Jan 27, 2007·The Cochrane Database of Systematic Reviews·J J Al SayyadA Jamal
Jun 1, 1983·Thorax·R J Davies

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