PMID: 9632746Jun 20, 1998Paper

Intranuclear distribution of HMGI/Y proteins. An immunocytochemical study

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
A M MartelliVincenzo Giancotti

Abstract

The intranuclear distribution of HMGI/Y proteins was analyzed by immunofluorescent staining in several cell lines using a polyclonal antibody that stained a fibrogranular network. In actively growing 3T3 fibroblasts, HMGI/Y proteins were mainly localized to heterochromatin masses, whereas in quiescent cells they were more diffusely distributed. Double labeling experiments showed a co-localization of HMGI/Y with DNA topoisomerase IIalpha. These results are in agreement with previously published biochemical data and indicate a possible involvement of HMGI/Y proteins in several nuclear functions, including chromatin organization and gene expression.

References

Jan 1, 1989·The Journal of Cell Biology·H Nakayasu, R Berezney
Aug 1, 1996·The Biochemical Journal·V GiancottiC Crane-Robinson
Jan 1, 1996·Progress in Nucleic Acid Research and Molecular Biology·M Bustin, R Reeves
Feb 1, 1997·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L M NeriA M Martelli

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Citations

Mar 6, 2010·Journal of the American Society for Mass Spectrometry·Nicolas L YoungBenjamin A Garcia
Nov 25, 2005·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Juliane BrieseAna-Maria Bamberger
May 4, 2004·Molecular and Cellular Biology·Frédéric CatezMichael Bustin
Jan 18, 2003·Journal of Cellular Biochemistry·Eddy S LemanRobert H Getzenberg
Sep 15, 2004·Journal of Chemical Neuroanatomy·Taiichi KatayamaMasaya Tohyama
Jun 24, 2004·Journal of Cell Science·Monika HarrerRobert Hock

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