Intraocular metastasis as a systemic presentation of neuroendocrine differentiation of prostate carcinoma.

Archivos de la Sociedad Española de Oftalmología
F J Valentín BravoR López Castro

Abstract

A 68 year-old male was referred for assessment of an amelanotic lesion in the right eye (RE) that was associated with a gradual loss of visual acuity (VA), of 2 months onset, as the main symptom. It was noted in his medical history, that 6 years ago, he had prostate cancer treated with prostatectomy, lymphadenectomy, and coadjuvant local radiotherapy (RT). He was asymptomatic until 6 months ago, when a metastasis was discovered in the left femur, which was treated with radiotherapy. There were no findings of interest in the left eye (LE). His VA was very low in his RE, and in the eye fundus examination a mass without pigment was observed in the posterior pole with an adjacent exudative retinal detachment. Due to his personal history and results of the complementary tests such as ultrasound and magnetic resonance, the most likely diagnostic option was metastasis of prostate carcinoma, subsequently being confirmed with the histopathology results. Despite 4 cycles of chemotherapy, the patient did not show any clinical or radiological response, worsening until his death 3 months later.

References

Jan 22, 2005·European Urology·Nadezda Vashchenko, Per-Anders Abrahamsson
Jan 6, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Akira KomiyaHideki Fuse
Apr 2, 2015·Indian Journal of Ophthalmology·Sruthi ArepalliCarol L Shields
Aug 21, 2018·Middle East African Journal of Ophthalmology·Carol L ShieldsJerry A Shields

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