PMID: 8586503Jan 1, 1995Paper

Intraocular pressure decrease after local ocular cooling is underestimated by applanation tonometry

International Ophthalmology
S OrgülP Hendrickson

Abstract

The effects of intense systemic or local cooling on aqueous humor dynamics in animals are an increased total outflow facility and a decreased aqueous flow. Few studies suggest that only vasoconstriction of arteriolar segments of the episcleral vasculature may be the cause for a decrease in intraocular pressure after local cooling in humans. Because corneal changes may have influenced such studies, the effect of local cooling was assessed in normal subjects. Intraocular pressure and corneal thickness were measured in 18 healthy human subjects before and after exposure of the right eye to both, an air stream at 20 degrees C, and an air stream at 0 degrees C. No significant changes in IOP or corneal thickness occurred under 20 degrees C conditions. After local cooling, the mean corneal thickness increased from 0.52 +/- 0.01 mm to 0.57 +/- 0.02 mm (p < 0.001). Mean intraocular pressure decreased from 13.8 +/- 2.9 mmHg to 12.9 +/- 3.1 mmHg (p < 0.026). The observed decrease in IOP correlated significantly but negatively (R = -0.53; p = 0.024) with the increase in corneal thickness, indicating that the cooling effect on IOP may be rather underestimated. The eye is very sensitive to local cooling effects, which may, however, partially...Continue Reading

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Citations

Apr 24, 2010·Indian Journal of Ophthalmology·M A ShamshadS Wahab
Feb 20, 2014·TheScientificWorldJournal·Marcella NebbiosoNicola Pescosolido
Mar 24, 2017·High Altitude Medicine & Biology·Gabriel WillmannAndreas Schatz
Jul 4, 2017·Journal of Glaucoma·William Foulsham, Andrew J Tatham
Aug 15, 2021·Experimental Eye Research·Christina M NicouChristopher L Passaglia

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