Intraocular pressure elevation after intravitreal or posterior sub-Tenon triamcinolone acetonide injection

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Yumiko YamamotoHisayuki Ueno

Abstract

Despite the benefits of intraocular steroids for the treatment of inflammatory, neovascular, proliferative, and edematous diseases, one of the side effects is raised intraocular pressure (IOP). In this study, we attempted to identify when IOP elevates, peaks, and returns to the preinjection baseline IOP after intravitreal or posterior sub-Tenon administration of triamcinolone acetonide, as well as the factors that might affect IOP. Retrospective case review was undertaken of 69 patients (82 eyes), who received either a 4 mg intravitreal (16 eyes) or a 20 mg posterior sub-Tenon (66 eyes) triamcinolone acetonide injection. IOP assessment for each eye was completed at the preinjection baseline and at the first, third, and sixth month of follow-up. The mean IOP of all eyes increased significantly at each follow-up. The mean maximum elevation ratio from the baseline was 4.0 (SD 5.2) mm Hg. An elevation of 5 mm Hg or greater occurred in 28 eyes (34.1%). The maximum elevation correlated significantly with age (p < 0.01). The incidence of an elevation of 5 mm Hg or greater was significantly higher among patients younger than 60 years (p < 0.01) and relatively higher among female patients (p = 0.051). The mean IOP increased significantl...Continue Reading

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Citations

Apr 23, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Ryosuke KawamuraKazuo Tsubota
Mar 11, 2011·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Ozgur YalcinbayirRemzi Avci
Mar 1, 2011·Archivos de la Sociedad Española de Oftalmología·M S FigueroaR Gil-Cazorla
Jun 19, 2013·Survey of Ophthalmology·Weerawat KiddeeYvonne M Buys
Feb 10, 2009·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Y AthanasiadisA Sharma
Dec 15, 2015·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Shaista GinyGonçalo Almeida
Oct 12, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Mehmet OkkaSüleyman Okudan
Jul 9, 2016·European Journal of Pharmacology·Adnan Dibas, Thomas Yorio
Jul 16, 2011·Ophthalmic Research·M Reza Razeghinejad, L Jay Katz
Dec 23, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A-M SeutheK T Boden
May 17, 2021·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Maryam AbtahiKarim F Damji
Feb 26, 2009·Current Opinion in Ophthalmology
Sep 29, 2021·Indian Journal of Ophthalmology·Dhananjay Shukla

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