Intraocular Pressure in Eyes Receiving Intravitreal Antivascular Endothelial Growth Factor Injections

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Vanessa LemosTeresa Gomes

Abstract

The aim of the this study was to determine the effect of intravitreal antivascular endothelial growth factor injections on intraocular pressure (IOP) and identify possible risk factors for the development of increased IOP. This prospective study included a total of 106 eyes receiving intravitreal injection of bevacizumab as treatment for macular edema or active choroidal neovascularization. IOP was measured by Goldmann applanation tonometry immediately before the intravitreal injection and 5 min, 1 h and 15 days after the procedure. The records of the study patients were reviewed for age, gender, history of glaucoma, diabetes mellitus, phakic status, systemic and topical medication and number of previous injections. Subconjunctival reflux was registered. IOP elevation was defined as IOP ≥21 mm Hg and/or a change from baseline of ≥5 mm Hg recorded at least on two or more measurements on the same visit. Mean preoperative IOP was 15.31 ± 3.90 mm Hg and postoperative IOP values were 27.27 ± 11.87 mm Hg (after 5 min), 17.59 ± 6.24 mm Hg (after 1 h) and 16.86 ± 3.62 mm Hg (after 15 days). The IOP variation was statistically significant between pre- and postoperative measurements (p < 0.05). Subconjunctival reflux was recorded in 11.3...Continue Reading

Citations

Apr 9, 2016·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Osman Çekiç, Semra Akkaya Turhan
Nov 26, 2016·Scientific Reports·Jiao TianLuosheng Tang
Jan 17, 2017·Journal of Pediatric Ophthalmology and Strabismus·Matthew D KarlDavid H Abramson
Feb 3, 2018·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Andrzej GrzybowskiUNKNOWN Euretina Board
Sep 20, 2017·Journal of Current Glaucoma Practice·Mónica LoureiroDália Meira
Apr 22, 2021·Clinical & Experimental Ophthalmology·Wedad S SalemSamantha Fraser-Bell

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