Intraoperative acceleromyographic monitoring reduces the risk of residual neuromuscular blockade and adverse respiratory events in the postanesthesia care unit

Anesthesiology
Glenn S MurphyMargarita Nisman

Abstract

Incomplete recovery from neuromuscular blockade in the postanesthesia care unit (PACU) may contribute to adverse postoperative respiratory events. This study determined the incidence and degree of residual neuromuscular blockade in patients randomized to conventional qualitative train-of-four (TOF) monitoring or quantitative acceleromyographic monitoring. The incidence of adverse respiratory events in the PACU was also evaluated. One hundred eighty-five patients were randomized to intraoperative acceleromyographic monitoring (acceleromyography group) or qualitative TOF monitoring (TOF group). Anesthetic management was standardized. TOF patients were extubated when standard criteria were met and no fade was observed during TOF stimulation. Acceleromyography patients had a TOF ratio of greater than 0.80 as an additional extubation criterion. Upon arrival in the PACU, TOF ratios of both groups were measured with acceleromyography. Adverse respiratory events during transport to the PACU and during the first 30 min of PACU admission were also recorded. A lower frequency of residual neuromuscular blockade in the PACU (TOF ratio < or = 0.9) was observed in the acceleromyography group (4.5%) compared with the conventional TOF group (30...Continue Reading

Associated Clinical Trials

References

Oct 1, 1992·Acta Anaesthesiologica Scandinavica·L I ErikssonA Johnson
Feb 1, 1992·Anesthesiology·H S Helbo-HansenL T Skovgaard
Sep 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M D DaleyA N Sandler
Nov 1, 1990·Anesthesiology·J T MollerS H Johansen
Jan 1, 1988·Acta Anaesthesiologica Scandinavica·J Viby-MogensenH K Nielsen
Oct 1, 1985·Anesthesiology·J Viby-MogensenB Chraemmer-Jørgensen
Aug 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·G D ShortenT Sieber
Sep 1, 1993·Chest·G B Russell, J M Graybeal
May 26, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·F Donati
May 4, 2000·British Journal of Anaesthesia·J Viby-Mogensen
Dec 26, 2001·Anesthesiology·Hans KirkegaardJames E Caldwell
Apr 12, 2002·Acta Anaesthesiologica Scandinavica·M R GätkeL T Skovgaard
Oct 24, 2002·British Journal of Anaesthesia·C McCaulA J McShane
May 28, 2005·Anesthesia and Analgesia·Glenn S MurphyJeffery S Vender
Sep 27, 2005·British Journal of Anaesthesia·C BaillardC M Samama
Jan 24, 2006·Anesthesia and Analgesia·Guy CammuThierry Deloof
Jan 2, 2007·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Thomas M Hemmerling, Nhien Le
Feb 20, 2007·British Journal of Anaesthesia·M NaguibJ E Ensor
Jul 10, 2007·British Journal of Anaesthesia·J Viby-MogensenL I Eriksson

❮ Previous
Next ❯

Citations

Apr 25, 2012·Der Anaesthesist·H AustD Rüsch
Apr 30, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·François Donati
Feb 15, 2012·Regional Anesthesia and Pain Medicine·Matthew C WylieCharles B Berde
Aug 26, 2011·Anesthesia and Analgesia·Rogerio L R Videira, Joaquim E Vieira
Jan 23, 2013·Anesthesia and Analgesia·Glenn S MurphyElizabeth Landry
Sep 25, 2014·Current Opinion in Anaesthesiology·Cynthia A Lien, Aaron F Kopman
Sep 25, 2014·Current Opinion in Anaesthesiology·Jan-Uwe Schreiber
Jan 21, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·M A BouderkaD Hamoudi
Jan 25, 2014·Journal of Clinical Monitoring and Computing·R Ross Kennedy
Jul 10, 2013·Journal of Anesthesia·Takashi Asai
May 3, 2011·Annales Françaises D'anesthèsie Et De Rèanimation·J AllaryJ-L Bourgain
Nov 15, 2008·Annales Françaises D'anesthèsie Et De Rèanimation·A SolisC Baillard
Mar 24, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·C Motamed, J-L Bourgain
Dec 23, 2014·Current Anesthesiology Reports·Hassan FarhanMatthias Eikermann
Mar 12, 2010·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Tom Heier
May 1, 2009·Expert Review of Neurotherapeutics·Rosemary M G Hogg, Rajinder K Mirakhur
Feb 13, 2016·British Journal of Anaesthesia·M Eikermann
Jan 21, 2016·British Journal of Anaesthesia·M Eikermann, T T Houle
Mar 5, 2013·Revista española de anestesiología y reanimación·M NortonF J Abelha
Mar 19, 2013·The Veterinary Clinics of North America. Equine Practice·Manuel Martin-Flores
Jan 12, 2016·Anaesthesia·G RodneyD R Ball
Jan 18, 2016·Revista española de anestesiología y reanimación·R Casans FrancésJ M Calvo Vecino
Jan 16, 2016·Brazilian Journal of Anesthesiology·Ismail AytacBayazit Dikmen
Apr 3, 2010·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·William Clayton Petty
Apr 3, 2010·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Satya Krishna Ramachandran, Denise O'Brien
Oct 27, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·A-A d'Hollander, J-L Bourgain
Apr 18, 2013·Critical Care Medicine·Steven B Greenberg, Jeffery Vender
Dec 9, 2015·Best Practice & Research. Clinical Anaesthesiology·Andreas GüldnerMarcelo Gama de Abreu
Feb 19, 2009·Anaesthesia·C ClaudiusJ Viby-Mogensen
Feb 19, 2009·Anaesthesia·A F Kopman, M Eikermann
Mar 26, 2009·Acta Anaesthesiologica Scandinavica·M Eikermann, L S Rasmussen
Nov 19, 2011·Acta Anaesthesiologica Scandinavica·H MirzakhaniA Nozari
Jun 22, 2010·Acta Anaesthesiologica Scandinavica·A R Baker, A B Baker
May 11, 2012·Acta Anaesthesiologica Scandinavica·H D de Boer, T Fuchs-Buder
Dec 7, 2011·Anaesthesia·S IsonoT C Mort
Jun 2, 2011·Veterinary Anaesthesia and Analgesia·Manuel Martin-FloresRobin D Gleed
Oct 21, 2009·Acta Anaesthesiologica Scandinavica·P Di MarcoP Pietropaoli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.