Intraoperative bone marrow puncture in breast cancer patients: prospective assessment of adverse side-effects

The Breast : Official Journal of the European Society of Mastology
Christoph DomschkeAlexander Scharf

Abstract

In breast cancer patients, intraoperative bone marrow puncture (BMP) with positive detection of disseminated tumor cells has been reported to predict unfavorable clinical outcome due to increased risk of recurrence. In this study, we prospectively assessed BMP-associated untoward side-effects. Fifty-eight consecutive breast cancer patients were prospectively explored after intraoperative BMP for postoperative pain (visual analogue scale, VAS) and complications in terms of infection, hematoma, and sensibility disorder. Furthermore, the impact of BMP on hospital stay duration was analyzed in 254 patients. In all subgroups analyzed, during five postoperative days patients complained about minor pain only at the site of BMP (VAS < 1) while the corresponding pain scores were significantly higher for the area of the operated breast. Post-BMP iliac crest hematomas were encountered in 13 out of 58 patients (22.4%) who were significantly older (p = 0.04), less frequently smokers (p = 0.02), and presented with higher body mass index (p = 0.01) than controls. Within the area of BMP no signs of infection or sensibility disorders were observed. Comparison of patients with and without BMP did not show any significant difference in postoperat...Continue Reading

References

Dec 1, 1979·Annals of the Rheumatic Diseases·J Scott, E C Huskisson
Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J L MansiR C Coombes
Feb 1, 1993·Applied Nursing Research : ANR·K A Herr, P R Mobily
Sep 12, 2003·Journal of Pain and Symptom Management·Philine VanhelleputteSteven Vanderschueren
Sep 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G WiedswangB Naume
Feb 24, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jean-Yves PiergaHenri Magdelénat
May 15, 2004·British Journal of Haematology·Vinod Devaliaf, Gareth Tudor
Aug 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Gro WiedswangBjørn Naume
Oct 16, 2004·Clinical and Laboratory Haematology·B J Bain
Mar 26, 2005·Journal of Clinical Pathology·B J Bain
Aug 27, 2005·The New England Journal of Medicine·Stephan BraunKlaus Pantel
May 15, 2007·Chest·Dilyara G YanbaevaEmiel F M Wouters

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.