Intraoperative cell transplantation for congestive heart failure: experience in China

Seminars in Thoracic and Cardiovascular Surgery
Hao ZhangSheng-shou Hu

Abstract

Despite significant improvement in the management of congestive heart failure (CHF), it still is a major worldwide public health problem. Currently, cell-based regenerative medicine has been developed as a promising therapeutic option for patients with CHF. Considering the large and growing population, it is estimated that over 5 million patients in China may need such a cell-based therapy to replace or repair the damaged myocardium. Cardiac surgery has emerged as an important player in heart cell therapy in China in recent years. Here, we summarize our achievements in both preclinical and clinical studies of intraoperative cell transplantation, and present our understanding of future research in this attractive field.

References

Nov 24, 1999·Circulation·R K LiT M Yau
Jun 18, 2003·Journal of Cardiac Surgery·Fumin ZhangRace L Kao
Sep 16, 2005·The New England Journal of Medicine·Jiang HePaul K Whelton
Oct 13, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Hao ZhangRen-Ke Li
Jan 26, 2006·Artificial Organs·Pingchuan ZhangShengshou Hu
Aug 8, 2006·International Journal of Cardiology·Mai HouSheng-shou Hu
Nov 3, 2007·The Journal of Thoracic and Cardiovascular Surgery·Hao ZhangSheng-shou Hu

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