PMID: 9451560Feb 6, 1998Paper

Intraoperative cytologic diagnosis of granulomas: a retrospective study of 156 cases

Diagnostic Cytopathology
I A Eltoum, S Tabbara

Abstract

To avoid contamination of equipment and reduce risks of infection, intraoperative cytology (IOC) is a useful substitute to conventional frozen section in the diagnosis of infectious diseases. One of the various histomorphologic patterns of infections is the granuloma, which sometimes may be difficult to diagnose cytologically. In an attempt to assess accuracy and pitfalls of IOC in the diagnosis of granuloma, cases diagnosed as granuloma on IOC or on permanent sections (PS) at George Washington University Medical Center were collected for the period of September 1990 to March 1996. Cyto-histologic correlation was performed. During that time, a diagnosis of granuloma in either the IOC or PS was rendered in 156 of 5,901 IOC cases. IOC showed definite granuloma (87), suspicious for granuloma (23), and neither definite nor suspicious for granuloma in 46 cases. The latter group corresponded to neoplasms (5) and benign conditions (41). Eighty-five cases were accurately diagnosed as definite granuloma by both IOC and PS. Fifty-seven cases diagnosed as granuloma by PS corresponded on IOC to suspicious for granuloma (11), benign smear (41), and neoplasms (5). Only two cases were incorrectly diagnosed as granuloma on IOC: a neoplasm and ...Continue Reading

References

Apr 1, 1978·Journal of Clinical Pathology·K C SuenP B Clement
Jul 1, 1991·American Journal of Clinical Pathology·M K Sidaway, S G Silverberg
Dec 1, 1987·American Journal of Clinical Pathology·J M EstebanS G Silverberg
Dec 1, 1995·Diagnostic Cytopathology·S G Silverberg

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Citations

May 7, 2002·Diagnostic Cytopathology·Yulin LiuStephen S Raab
Dec 7, 2005·Archives of Pathology & Laboratory Medicine·Mamoun Younes

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