Intraoperative extracorporeal irradiation for limb sparing in 13 dogs

Veterinary Surgery : VS
Julius M LiptakS J Withrow

Abstract

To evaluate extracorporeal intraoperative radiation therapy (IORT) as a treatment method for limb and joint sparing in dogs with appendicular sarcomas in sites other than the distal aspect of the radius. Retrospective study. Thirteen client-owned dogs. The bone tumor database and medical records (1998-2002) were reviewed for dogs with primary appendicular bone tumors treated with IORT limb-sparing surgery and adjuvant chemotherapy. The segment of bone containing the tumor was isolated from adjacent soft tissue and an osteotomy performed distant to the tumor. The bone segment was exteriorized, irradiated (70 Gy single fraction), and then stabilized with internal fixation. Adjuvant chemotherapy was administered. Lameness was graded and local and distant tumor control was determined. Associations between intra- and postoperative variables with complications and Kaplan-Meier survival analysis for median disease-free interval and survival time were calculated. Limb function was good or excellent in 10 dogs (77%). Postoperative complications (9 dogs, 69%) included deep infection, fracture of the irradiated bone, and implant failure. Surgical failure was more likely if a single implant was used to stabilize the osteotomized bone and i...Continue Reading

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Citations

Feb 22, 2005·Veterinary Surgery : VS·Julius M LiptakStephen J Withrow
Oct 2, 2013·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·A Renwick, E Scurrell
Mar 25, 2011·Indian Journal of Orthopaedics·Sridhar VijayanTimothy Wr Briggs
Jun 18, 2014·ILAR Journal·Joelle M FengerWilliam C Kisseberth
Feb 8, 2016·The Veterinary Clinics of North America. Small Animal Practice·Lisa J Forrest
Sep 1, 2005·The Veterinary Clinics of North America. Small Animal Practice·Ruthanne Chun
Feb 19, 2009·Veterinary and Comparative Oncology·A CoomerD Lurie
Jan 8, 2014·Veterinary Surgery : VS·Jennifer L CoveyRowan J Milner
Mar 21, 2017·Veterinary Surgery : VS·Tanya C GarciaSusan M Stover
Nov 24, 2018·Veterinary Surgery : VS·Bernard SéguinLaura E Selmic
Mar 5, 2009·The Journal of Bone and Joint Surgery. British Volume·A H KriegP D Stalley
Feb 6, 2017·Veterinary Surgery : VS·Michele A SteffeySusan M Stover
Jul 10, 2019·The Journal of Veterinary Medical Science·Minori AkasakaManabu Mochizuki
Jan 7, 2021·Veterinary and Comparative Oncology·Tiffany Wormhoudt MartinSusan M LaRue

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