Intraoperative hypothermia during cytoreductive surgery for ovarian cancer and perioperative morbidity

Obstetrics and Gynecology
Mehdi Moslemi-KebriaWilliam A Cliby

Abstract

To evaluate intraoperative hypothermia as a predictor for morbidity after open abdominal surgery for ovarian cancer. This cohort study included 146 women with stage IIIC and IV ovarian cancer who underwent debulking surgery at our institution from January 1, 2001, through December 31, 2003. Hypothermia was defined as end operative temperature lower than 36°C. Early complications (occurring within 30 days of surgery) included: mortality, infectious morbidities, cardiovascular events, venous thromboembolic (VTE) events, anastomotic leak, readmission, and reoperation. Survival was also evaluated. Logistic regression models were used to adjust for known confounders. The mean age was 63.9 ± 11.7 years; 46 (32%) patients had a body mass index higher than 30; mean operative time was 239 ± 85 minutes. There were five deaths perioperatively, all in the hypothermic group. Hypothermia was associated with an increased risk of any early complications (34 [42.0%] compared with 11 [16.9%]) with an adjusted odds ratio (OR) of 3.40 (95% confidence interval [CI] 1.48-8.33). For individual complications, hypothermic patients were at higher risk for VTE events with an adjusted OR of 3.53 (95% CI 1.02-16.44); infectious morbidity with an adjusted O...Continue Reading

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Citations

Jan 4, 2013·British Journal of Anaesthesia·A Heaney, D J Buggy
Jul 23, 2013·Anesthesia and Analgesia·Hector J LacassieGhislaine C Echevarría
Oct 9, 2014·Advances in Surgery·Ira L LeedsGenevieve B Melton
Aug 14, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Ninnie Borendal Wodlin, Lena Nilsson
Apr 13, 2013·Gynecologic Oncology·Eleftheria KalogeraWilliam A Cliby
Sep 5, 2018·Journal for Immunotherapy of Cancer·Orneala BakosLee-Hwa Tai
Mar 14, 2018·BMC Cancer·Lee-Hwa TaiRebecca C Auer
Aug 9, 2020·Pediatric Quality & Safety·Jessica A CroninEugenie Heitmiller
Sep 2, 2020·International Journal of Surgery·Zong Xuan LeeIna Ismiarti Binti Shariffuddin
Sep 3, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Martin HübnerGregg Nelson
Jul 10, 2019·Gynecologic Oncology·Amanika KumarSean C Dowdy

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