Intraoperative intermittent neuromonitoring of inferior laryngeal nerve and staged thyroidectomy: our experience

Endocrine
Ottavio CavicchiGianlorenzo Dionigi

Abstract

To evaluate the reliability of intermittent intraoperative neuromonitoring (I-IONM) through recurrent laryngeal nerve (RLN) stimulation and laryngeal palpation in predicting postoperative vocal cord palsy and to examine the reliability of this technique in providing useful information in the decision to perform a staged surgery in initially planned total thyroidectomy. This was a retrospective cohort study of patients who underwent thyroid surgery at the ENT Department of the University of Bologna from January 2014 to June 2017. In all cases, preoperative and postoperative laryngoscopy was performed. All surgeries were conducted with I-IONM and RLN simultaneous laryngeal palpation (NSLP) to detect contraction (laryngeal twitch) of the posterior crico-arytenoid muscle. The incidence of vocal cord palsy was calculated for nerves at risk. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV), positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were calculated with a confidence interval determined at 95% level. Seven hundred and sixteen patients were enrolled in the study. The incidence of vocal cord palsy was 3.16%. Specificity of I-IONM in predicting vocal cord p...Continue Reading

References

Jan 1, 1991·Journal of Clinical Epidemiology·D L SimelD B Matchar
Dec 20, 2002·Thyroid : Official Journal of the American Thyroid Association·Gregory W Randolph, Gilbert H Daniels
Oct 1, 2004·World Journal of Surgery·Gregory W RandolphJamie Wilkins
Dec 25, 2007·Journal of the American College of Surgeons·Samuel K SnyderJohn W Roberts
Apr 2, 2009·International Journal of Clinical Practice·J-P JeannonR Simo
May 27, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ottavio CavicchiOttavio Piccin
Oct 23, 2009·American Journal of Clinical Pathology·Edmund S CibasUNKNOWN NCI Thyroid FNA State of the Science Conference
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Feb 14, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·Claudio R CerneaJosé Brandão
Jun 15, 2012·The British Journal of Surgery·H DralleA Machens
Nov 28, 2012·Langenbeck's Archives of Surgery·Magnus MelinPeter E Goretzki
Dec 20, 2012·Thyroid : Official Journal of the American Thyroid Association·Samira Mercedes SadowskiFrederic Triponez
Mar 7, 2013·Thyroid : Official Journal of the American Thyroid Association·Gianlorenzo Dionigi, Francesco Frattini
Jun 14, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sujana S ChandrasekharUNKNOWN American Academy of Otolaryngology-Head and Neck Surgery
Jan 21, 2015·The Laryngoscope·Tatyana E FontenotEmad Kandil
May 31, 2015·Acta otorrinolaringológica española·José Luis Pardal-Refoyo, Carlos Ochoa-Sangrador
Oct 22, 2016·JAMA Otolaryngology-- Head & Neck Surgery·Ioannis VasileiadisGregory Kouraklis
May 17, 2017·International Journal of Surgery·Pietro Giorgio CalòAngelo Nicolosi

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Citations

Feb 24, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kai-Ning LuDing-Cun Luo

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