Intraoperative Lung-Protective Ventilation Trends and Practice Patterns: A Report from the Multicenter Perioperative Outcomes Group

Anesthesia and Analgesia
S Patrick BenderSachin Kheterpal

Abstract

The use of an intraoperative lung-protective ventilation strategy through tidal volume (TV) size reduction and positive end-expiratory pressure (PEEP) has been increasingly investigated. In this article, we describe the current intraoperative lung-protective ventilation practice patterns and trends. By using the Multicenter Perioperative Outcomes Group database, we identified all general endotracheal anesthetics from January 2008 through December 2013 at 10 institutions. The following data were calculated: (1) percentage of patients receiving TV > 10 mL/kg predicted body weight (PBW); (2) median initial and overall TV in mL/kg PBW and; (3) percentage of patients receiving PEEP ≥ 5 cm H2O. The data were analyzed at 3-month intervals. Interinstitutional variability was assessed. A total of 330,823 patients met our inclusion criteria for this study. During the study period, the percentage of patients receiving TV > 10 mL/kg PBW was reduced for all patients (26% to 14%) and in the subpopulations of obese (41% to 25%), short stature (52% to 36%), and females (39% to 24%; all P values <0.001). There was a significant reduction in TV size (8.90-8.20 mL/kg PBW, P < 0.001). There was also a statistically significant but clinically irrel...Continue Reading

References

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Jul 1, 2006·Anesthesiology·Evans R Fernández-PérezOgnjen Gajic
Nov 22, 2011·Best Practice & Research. Clinical Anaesthesiology·Robert E Freundlich, Sachin Kheterpal
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Nov 8, 2013·The New England Journal of Medicine·Emmanuel FutierSamir Jaber
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Oct 11, 2014·BMC Anesthesiology·Dharshi KaralapillaiRinaldo Bellomo

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Citations

Dec 19, 2017·Anesthesia and Analgesia·S Patrick Bender, William G Tharp
Aug 2, 2017·Anesthesia and Analgesia·Karim S LadhaMatthias Eikermann
Dec 12, 2017·International Anesthesiology Clinics·Jayashree K Raikhelkar, James M Blum
Dec 12, 2017·International Anesthesiology Clinics·S Patrick BenderAriel Bensimhon
Feb 27, 2019·JAMA : the Journal of the American Medical Association·Eric SunUNKNOWN Multicenter Perioperative Outcomes Group (MPOG)
Sep 18, 2018·Anesthesia and Analgesia·Maximilian S SchaeferTanja Astrid Meyer-Treschan
Dec 14, 2018·AACN Advanced Critical Care·John J Gallagher
Nov 14, 2018·Intensive Care Medicine·Emily A VailHannah Wunsch
Apr 18, 2020·Drugs & Aging·Eric Y ChenRobert B Schonberger
Nov 15, 2017·Journal of Anesthesia·Chirag K ShahAna Fernandez-Bustamante
Nov 16, 2018·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Annemarie AkkermansLeif Saager
Dec 4, 2019·Anesthesiology·Michael R MathisUNKNOWN Multicenter Perioperative Outcomes Group Investigators
Feb 20, 2021·European Journal of Anaesthesiology·Sunny G NijbroekUNKNOWN LAS VEGAS study investigators, the PROVE Network and the Clinical Trial Network of the European Society of Anaesthesiology

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