Intraoperative magnetic resonance imaging assessment of non-functioning pituitary adenomas during transsphenoidal surgery

Pituitary
Kunal S PatelClark C Chen

Abstract

To review the utility of intraoperative imaging in facilitating maximal resection of non-functioning pituitary adenomas (NFAs). We performed an exhaustive MEDLINE search, which yielded 5598 articles. Upon careful review of these studies, 31 were pertinent to the issue of interest. Nine studies examined whether intraoperative MRI (iMRI) findings correlated with the presence of residual tumor on MRI taken 3 months after surgical resection. All studies using iMRI of >0.15T showed a ≥90% concordance between iMRI and 3-month post-operative MRI findings. 24 studies (22 iMRI and 2 intraoperative CT) examined whether intraoperative imaging improved the surgeon's ability to achieve a more complete resection. The resections were carried out under microscopic magnification in 17 studies and under endoscopic visualization in 7 studies. All studies support the value of intraoperative imaging in this regard, with improved resection in 15-83% of patients. Two studies examined whether iMRI (≥0.3T) improved visualization of residual NFA when compared to endoscopic visualization. Both studies demonstrated the value of iMRI in this regard, particularly when the tumor is located lateral of the sella, in the cavernous sinus, and in the suprasellar ...Continue Reading

References

Aug 1, 1995·Journal of Neurosurgery·Z RamE H Oldfield
Jul 1, 1994·Radiology·J L DoppmanE H Oldfield
Feb 13, 2001·Journal of Magnetic Resonance Imaging : JMRI·R S PergolizziF A Jolesz
Sep 22, 2001·Journal of Neurosurgery·R FahlbuschC Nimsky
Sep 25, 2001·The Laryngoscope·J C Dort, G R Sutherland
Nov 25, 2004·Neurosurgery Clinics of North America·Borimir J DarakchievRonald E Warnick
Sep 8, 2006·American Journal of Rhinology·Vijay K AnandAshutosh Kacker
Oct 14, 2009·Neurosurgical Review·Fabian BaumannRené-Ludwig Bernays
Sep 6, 2011·Clinical Neurology and Neurosurgery·Todd W VitazChristopher J Carrubba
Aug 16, 2014·Journal of Neurosurgery·Sven BerkmannMichael Buchfelder

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Citations

Jul 4, 2018·Endocrine Connections·Morten Winkler MøllerFrantz Rom Poulsen
Jan 18, 2018·The British Journal of Surgery·M A StammesJ S D Mieog
Apr 19, 2019·Der Nervenarzt·Jürgen HoneggerSabrina Giese
Feb 22, 2021·Journal of Neuro-oncology·Navid RedjalBrian V Nahed

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