Intraosseous infusion rates under high pressure: a cadaveric comparison of anatomic sites

The Journal of Trauma and Acute Care Surgery
Jason PasleyDeborah M Stein

Abstract

When traditional vascular access methods fail, emergency access through the intraosseous (IO) route can be lifesaving. Fluids, medications, and blood components have all been delivered through these devices. We sought to compare the performance of IO devices placed in the sternum, humeral head, and proximal tibia using a fresh human cadaver model. Commercially available IO infusion devices were placed into fresh human cadavers: sternum (FAST-1), humeral head (EZ-IO), and proximal tibia (EZ-IO). Sequentially, the volume of 0.9% saline infused into each site under 300 mm Hg pressure over 5 minutes was measured. Rates of successful initial IO device placement and subjective observations related to the devices were also recorded. For 16 cadavers over a 5-minute bolus infusion, the total volume of fluid infused at the three IO access sites was 469 (190) mL for the sternum, 286 (218) mL for the humerus, and 154 (94) mL for the tibia. Thus, the mean (SD) flow rate infused at each site was as follows: (1) sternum, 93.7 (37.9) mL/min; (2) humerus, 57.1 (43.5) mL/min; and (3) tibia, 30.7 (18.7) mL/min. The tibial site had the greatest number of insertion difficulties. This is the first study comparing the rate of flow at the three most c...Continue Reading

References

Jan 1, 1987·The Journal of Emergency Medicine·R M McNamaraD R Malone
Sep 1, 1985·Annals of Emergency Medicine·V A RosettiC Aprahamian
Feb 1, 1994·Annals of Emergency Medicine·C M SimmonsD van Stralen
Feb 1, 1993·Journal of Pediatric Surgery·J GuyS J Zuspan
Jul 1, 1993·Annals of Emergency Medicine·P W GlaeserD S Smith
Feb 1, 1997·The Journal of Trauma·M Waisman, D Waisman
Apr 27, 2000·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·A MacnabM Whelan
May 8, 2001·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·M W Hubble, D C Trigg
Jun 12, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·M. Yousuf HasanSuzanne P. Murphy
Oct 21, 2003·The Journal of Trauma·Douglas M G BowleyGraeme J Pitcher
Jul 13, 2004·Resuscitation·Michael Clem, Paul Tierney
Dec 16, 2006·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Raymond FowlerMarvin Wayne
Aug 19, 2007·The Annals of Pharmacotherapy·Marcia L BuckJefferson M Sesler
Jul 16, 2008·Journal of the Royal Army Medical Corps·B R CooperA Mellor
Dec 2, 2008·The American Journal of Emergency Medicine·Marcus Eng Hock OngAdeline Su-Yin Ngo
Sep 11, 2009·The Journal of Trauma·James H PaxtonHoward A Klausner
Jan 17, 2012·The American Journal of Emergency Medicine·Boon Kiat Kenneth TanMarcus Eng Hock Ong
Dec 4, 2012·Emergency Medicine Clinics of North America·Gemma C LewisJefferson G Williams

❮ Previous
Next ❯

Citations

Aug 27, 2015·The Journal of Trauma and Acute Care Surgery·Niels Hammer, Michael Bernhard
Aug 27, 2015·The Journal of Trauma and Acute Care Surgery·Jason Pasley
Jun 30, 2016·The American Journal of Emergency Medicine·Anna Drozd, Marcin Madziała
Jun 28, 2016·The American Journal of Emergency Medicine·Thompson KehrlRobert A Jones
Nov 22, 2016·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Avi ShinaAvraham Yitzhak
Jun 21, 2017·Resuscitation·Bryan A FeinsteinPeter J Kudenchuk
May 6, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mohammad W KassemR Shane Tubbs
Feb 15, 2019·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Renate SørgjerdJon-Kenneth Heltne
Feb 23, 2020·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Joseph Antony TylerHenry Dudley De'Ath
Apr 15, 2020·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
Apr 15, 2016·Critical Care : the Official Journal of the Critical Care Forum·F PetitpasO Mimoz
Oct 15, 2019·Frontiers in Veterinary Science·James LangeAylin Atilla
Dec 27, 2016·Case Reports in Critical Care·Mridula KrishnanIlya Berim
Aug 25, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mohammad W KassemR Shane Tubbs
Oct 3, 2018·Clinical and Experimental Emergency Medicine·Cliff ReidGeoff Healy
Mar 8, 2019·Scientific Reports·Marion WiegeleEva Schaden
Oct 11, 2019·The Journal of Surgical Research·Jonathan D AutenGreg J Zarow
Jun 22, 2021·The Journal of Surgical Research·Eric SulavaJonathan D Auten

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors
Julio LairetJames King
The American Journal of Emergency Medicine
Marcus Eng Hock OngAdeline Su-Yin Ngo
© 2022 Meta ULC. All rights reserved