Intraosseous schwannoma of the mobile spine: a report of twenty cases

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Yong Qiang WangZhong Jun Liu

Abstract

To clarify the clinical features, surgical strategies, and outcomes of intraosseous schwannoma (IOS) of the mobile spine. We retrospectively reviewed patients with primary benign spinal schwannoma who underwent surgery in our orthopedic department. A total of 101 patients with primary benign schwannoma located in the mobile spine underwent surgery in our orthopedic department from 2005 to 2015. Twenty-five patients presented with aggressive features. Twenty patients were regularly followed up, twelve with lesions in the cervical spine, six with lesions in the thoracic region, and two with lesions in the lumbar spine. Preoperative CT-guided biopsy was performed in fourteen cases; the accuracy of diagnosis was 100%, and IOS is not histologically different from conventional schwannoma. The computed tomography (CT) scan revealed expansile and osteolytic bone destruction in all these cases, with six patients having pathological fracture. On T2-weighted magnetic resonance imaging, the lobulated schwannomas showed heterogeneous signal intensity and significant heterogeneous enhancement on post-contrast images. Gross total resection was performed in seventeen patients and subtotal resection in three. Tumor-involved nerve roots resectio...Continue Reading

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Citations

Apr 28, 2020·World Journal of Clinical Cases·Zhong-Qi XuHao-Tao Yu
Apr 23, 2021·Journal of Neurointerventional Surgery·Giorgos D MichalopoulosMohamad Bydon

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