Intrapancreatic accessory spleen: a diagnostic dilemma

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Bing-Qi LiJun-Chao Guo

Abstract

As intrapancreatic accessory spleen (IPAS) is rarely encountered during clinical practice, the aim of this review was to summarize the epidemiologic features, the diagnosis and treatment of IPAS. MEDLINE and EMBASE were searched for articles reporting on IPAS. Categorical variables were reported as frequency and percentage. Continuous variables were reported as median (range). A total of 105 patients were included, of which 73% were detected incidentally. The male/female ratio was 1.23. The size of IPAS in patients who had previously undergone splenectomy was larger than that of patients without prior splenectomy (2.5 cm vs 1.5 cm; p = 0.020). No preoperative examination was able to make a definite diagnosis for all IPASs. More than half of the patients (55%) received surgical treatment, most of which (87%) were suspected as pancreatic neuroendocrine tumors (p-net) preoperatively. Although rare, IPAS should be considered in the differential of patients with suspected incidental p-net, especially if there has been a past history of splenectomy. Preoperative diagnosis is important as unnecessary surgery can be avoided. As it is difficult to make a definite diagnosis of IPAS by one single examination, multiple techniques may be re...Continue Reading

Citations

Jun 4, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Victoria R RendellScott B Reeder
Mar 10, 2020·Clinical Nuclear Medicine·Thien Vinh LuongAnne Kirstine Arveschoug
Jun 20, 2020·International Journal of Surgical Pathology·W CheukJ K C Chan
Jul 11, 2019·World Journal of Surgical Oncology·Francesco LancellottiPiero Chirletti
Mar 23, 2019·BMJ Case Reports·Namita ChavanPrasad Wagle
Feb 28, 2019·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·UNKNOWN Grupo de Trabajo de Aparato Digestivo en Enfermedades BiliopancreáticasAna Barbado Cano
Jul 10, 2019·Acta Radiologica Open·Maria Zurek Munk-MadsenGro Linno Willemoe

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