Intrapartum epidural analgesia and low Apgar score among singleton infants born at term: A propensity score matched study

Acta Obstetricia Et Gynecologica Scandinavica
Anita C J RavelliJoris A M van der Post

Abstract

The associations of epidural analgesia and low Apgar score found in the Swedish Registry might be a result of confounding by indication. The objective of this study was to assess the possible effect of intrapartum epidural analgesia on low Apgar score and neonatal intensive care unit (NICU) admission in term born singletons with propensity score matching. This was a propensity score matched study (n = 257 872) conducted in a national cohort of 715 449 term live born singletons without congenital anomalies in the Netherlands. Mothers with prelabor cesarean section were excluded. Main outcome measures were 5-minute Apgar score <7, 5-minute Apgar score <4 and admission to a NICU for at least 24 hours. First, an analysis of the underlying risk factors for low Apgar score <7 was performed. Multivariable analyses were applied to assess the effect of the main risk factor, intrapartum epidural analgesia, on low Apgar score to adjust the results for confounding factors. Second, a propensity score matched analysis on the main risk factors for epidural analgesia was applied. By propensity score matching the (confounding) characteristics of the women who received epidural analgesia with the characteristics of the control women without epid...Continue Reading

References

Nov 26, 1991·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R DespratsG Pontonnier
Feb 15, 2001·The New England Journal of Medicine·B M CaseyK J Leveno
Jun 30, 2001·Obstetrics and Gynecology·K Thorngren-Jerneck, A Herbst
Apr 20, 2006·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Linda HoganAndreas Herbst
Aug 12, 2008·Methods of Information in Medicine·M TrompG J Bonsel
Mar 31, 2009·European Journal of Clinical Pharmacology·Luciana de Barros DuarteSérgio Pereira da Cunha
May 7, 2009·Journal of Epidemiology and Community Health·A C J RavelliG J Bonsel
Feb 1, 2012·Pediatrics·Elizabeth A GreenwellEllice Lieberman
Sep 22, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Annemieke C C EversAnneke Kwee
Oct 31, 2013·Archives of Disease in Childhood. Fetal and Neonatal Edition·Manoj KumarAmbikaipakan Senthilselvan
Feb 15, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·M P Ward Platt
May 2, 2014·Health Services Research·Melissa M GarridoMelissa D Aldridge
May 30, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sabine EnsingAnita C J Ravelli
May 27, 2015·European Journal of Epidemiology·Maria AltmanOlof Stephansson
Jan 1, 2016·Journal of Epidemiology and Community Health·Jennifer ZeitlinUNKNOWN Euro-Peristat Scientific Committee
Jan 23, 2016·Lancet·Vicki FlenadyUNKNOWN Lancet Stillbirths In High-Income Countries Investigator Group
May 12, 2017·Paediatric and Perinatal Epidemiology·Sven CnattingiusThomas Frisell
Feb 14, 2018·BMJ : British Medical Journal·Martina PerssonSven Cnattingius
Dec 24, 2018·American Journal of Obstetrics and Gynecology·Liset HoftiezerRichard A van Lingen

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Methods Mentioned

BETA
SGA
cesarean section

Software Mentioned

SAS
R

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