Intraperitoneal chemotherapy: a reemerging approach in the treatment of ovarian cancer

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
Barbie Drake

Abstract

Infusion of chemotherapy drugs through an intraperitoneal access device into the peritoneal cavity has reemerged as an approach that provides improved outcomes for patients with ovarian and other primary peritoneal cancers. This method allows for high concentrations of chemotherapy drugs to contact the tumor, surrounding tissues, and adjacent organs directly. The semipermeable membrane of the peritoneal cavity acts as a barrier and limits the passage of drugs in and out of the systemic circulation, thereby decreasing toxicity. This article discusses the physiology of peritoneal drug absorption, indications for use, the adverse effect profile and complications, and the administration technique.

References

Jan 22, 2005·Oncology Nursing Forum·Oswald A StuartPaul H Sugarbaker
Jan 6, 2006·The New England Journal of Medicine·Deborah K ArmstrongUNKNOWN Gynecologic Oncology Group
Feb 8, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Maurie Markman, Joan L Walker
Jun 19, 2007·Clinical Journal of Oncology Nursing·Virginia R Martin
Jun 19, 2007·Clinical Journal of Oncology Nursing·Lois Almadrones
Jun 19, 2007·Clinical Journal of Oncology Nursing·Catherine Hydzik
Dec 8, 2007·Clinical Journal of Oncology Nursing·Keith MarinPaula Muehlbauer
May 2, 2008·The Oncologist·Ignace VergotePatrick Berteloot

❮ Previous
Next ❯

Citations

Dec 2, 2015·Experimental and Therapeutic Medicine·Ming-Xin RenHai-Yan Song

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved