Intraperitoneal mesh devices for small midline hernias: mesh behavior in a porcine model

Hernia : the Journal of Hernias and Abdominal Wall Surgery
E ReynvoetFrederik Berrevoet

Abstract

Although clinical data on long-term efficacy are lacking, the use of self-expanding devices for intraperitoneal placement in the management of small midline hernias has been popularized. In the present experimental study, two different devices were investigated regarding tissue ingrowth, adhesion formation and solid mesh placement. Two devices of 4.3 cm diameter, one ePTFE-containing small pore polypropylene mesh (PP/ePTFE) and a multi-layered large-pore polypropylene patch with an oxidized cellulose anti-adhesive barrier (PP/ORC), both containing a self-deployment system, were placed intraperitoneally at the linea alba of 24 female pigs. A first laparoscopy was performed to evaluate mesh positioning against the abdominal wall. 1 (n = 6), 2 (n = 6), 4 (n = 6) and 12 weeks (n = 6) later, mesh appearance was inspected and adhesion formation was assessed. All meshes were excised for histological evaluation. Folding of the patch was more frequently observed at PP/ePTFE, yet no excessive cupping was noticed. Adhesions predominantly presented at short-term evaluation. Overall adhesion formation at all samples was significantly more extensive for PP/ORC (p = 0.048). Massive shrinkage was observed for PP/ORC: after a 12-week period 22%...Continue Reading

References

Oct 2, 2001·The British Journal of Surgery·A ArroyoR Calpena
May 14, 2005·Hernia : the Journal of Hernias and Abdominal Wall Surgery·P SanjayA Woodward
Jul 27, 2005·Hernia : the Journal of Hernias and Abdominal Wall Surgery·J A HalmW F Weidema
Jul 26, 2006·Surgical Endoscopy·J W A BurgerJ Jeekel
May 8, 2007·The Journal of Surgical Research·Tammo S de Vries ReilinghRobert P Bleichrodt
Mar 1, 2008·Hernia : the Journal of Hernias and Abdominal Wall Surgery·D F MartinG R Voeller
Feb 19, 2009·The British Journal of Surgery·M H F SchreinemacherN D Bouvy
Apr 28, 2010·World Journal of Surgery·Frederik BerrevoetBernard de Hemptinne
Jun 12, 2010·American Journal of Surgery·Frederik BerrevoetBernard de Hemptinne
Jun 18, 2010·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F E MuysomsP Pletinckx
Jul 17, 2010·Hernia : the Journal of Hernias and Abdominal Wall Surgery·N Aslani, C J Brown
Sep 22, 2010·Hernia : the Journal of Hernias and Abdominal Wall Surgery·E IversenL N Jorgensen
Nov 6, 2010·Digestive Surgery·Karina VychnevskaiaJean-Pierre Arnaud
Dec 16, 2011·Hernia : the Journal of Hernias and Abdominal Wall Surgery·P R CarterB W Allain
Jul 25, 2013·Hernia : the Journal of Hernias and Abdominal Wall Surgery·J BontinckF Muysoms

❮ Previous
Next ❯

Citations

Aug 16, 2016·Hernia : the Journal of Hernias and Abdominal Wall Surgery·S HarsløfH Friis-Andersen
Sep 25, 2017·Plastic and Reconstructive Surgery·Sumanas W JordanGregory A Dumanian
Nov 6, 2018·Hernia : the Journal of Hernias and Abdominal Wall Surgery·J L PorreroA J Torres
Sep 19, 2019·Acta Cirúrgica Brasileira·Rogério Aoki FuziyMarcelo Moura Linhares

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.