Intraperitoneal microdialysis in the postoperative surveillance of infants undergoing surgery for congenital abdominal wall defect: A pilot study

Journal of Pediatric Surgery
Kirsten RisbyNiels Qvist

Abstract

This study aims to investigate the safety and clinical implication of intraperitoneal microdialysis (MD) in newborns operated on for congenital abdominal wall defect. 13 infants underwent intraperitoneal microdialysis (9 with gastroschisis and 4 with omphalocele). MD samples were collected every four hours and the concentrations of lactate, glycerol, glucose and pyruvate were measured. The results of MD were compared between the group of infants with gastroschisis and the group with omphalocele. The duration of parenteral nutrition and tube feeding were compared for high and low levels of intraperitoneal lactate, glycerol, and glucose and lactate/pyruvate ratio respectively. High and low levels were defined as above or below the median value on day one. Results from intraperitoneal MD showed a significantly higher mean lactate concentration in the group of infants with gastroschisis compared with the group of infants with omphalocele. The median values were 6.19mmol/l and 2.19mmol/l, respectively (P=0.006). The results from MD in the six infants in the gastroschisis group who underwent secondary closure after Silo treatment were similar to those who underwent primary closure. None of the infants with omphalocele received parent...Continue Reading

References

Oct 1, 1991·Journal of Internal Medicine·U Ungerstedt
Apr 19, 2003·Pediatric Surgery International·S J SinghD Cass
Nov 7, 2007·Pediatric Surgery International·Katharina HenrichPeter G Weber
Mar 12, 2009·Pediatric Surgery International·Ryan P DavisGeorge B Mychaliska
May 13, 2009·Journal of Pediatric Surgery·Nathaniel R PayneR Hampton Rich
May 19, 2012·The Surgical Clinics of North America·Daniel J Ledbetter
Jun 19, 2012·Journal of Pediatric Surgery·Kyle N CowanUNKNOWN Canadian Pediatric Surgery Network

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Citations

Sep 26, 2016·Journal of Pediatric Surgery·Kirsten RisbyMarianne S Jakobsen
Nov 28, 2018·World Journal of Surgery·Jonas Emil SabroeMark Bremholm Ellebæk

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