Intrapulmonary unicentric Castleman disease mimicking peripheral pulmonary malignancy

Thoracic Cancer
Yi LiuJun Chen

Abstract

Castleman disease, also known as angiofollicular lymph node hyperplasia, can manifest as a unicentric or multicentric disorder. Intrapulmonary Castleman disease is very rare. Here, we present a patient with intrapulmonary Castleman disease who underwent left upper pulmonary lobectomy for suspected early lung cancer. The histopathologic diagnosis of the lobar mass was hyaline-type Castleman disease. The patient has remained well after surgery, showing no local recurrence or distant disease during a two-year follow-up period. Although unicentric Castleman disease originating in the lung is rare, it should be considered in the differential diagnosis of primary pulmonary malignant tumors.

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Citations

Oct 11, 2016·Journal of Cancer Research and Therapeutics·Tao Wang, Yang Liu
Sep 9, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Paula Fernández-RodríguezJosé Manuel Jiménez-Hoyuela García
Jan 11, 2017·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·C PaaschM Strik
Jun 12, 2019·Surgical Case Reports·Masaya AokiMasami Sato
Jun 27, 2020·Seminars in Diagnostic Pathology·Ha Nguyen, Joo Y Song

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Related Concepts

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Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.

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