Intrasellar plasmacytoma: an unusual presentation of multiple myeloma

Acta neurochirurgica
E YamanS Buyukberber

Abstract

Plasmacytomas are unusual causes of a sellar mass. Occasionally, they can be misdiagnosed as a nonfunctioning adenoma because of radiological and clinical similarities. We reviewed the pertinent literature and discuss here in the light of an illustrative case of our own. A 70-year-old woman presented with a recurrent hypophysial mass. Initial diagnosis of a nonfunctioning pituitary adenoma was later overruled by a repeat biopsy, which showed a plasmacytoma. The tumor stained positively for CD138 and kappa light chain. Further studies confirmed the diagnosis of multiple myeloma. The patient was successfully treated with radiotherapy followed by systemic chemotherapy. Because they have different therapeutic implications, extramedullary plasmacytomas involving pituitary gland should be considered in the differential diagnosis of a nonfunctioning pituitary mass.

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Citations

Oct 12, 2011·Pituitary·Rene Joukhadar, Ken Chiu
Nov 25, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Imad Saeed KhanAnil Nanda
Nov 18, 2011·Neuro-Chirurgie·F LakhdarA El Khamlichi
Jun 11, 2016·Endocrinology, Diabetes & Metabolism Case Reports·Anne SoejbjergUlla Kampmann
Dec 6, 2017·Endocrinology, Diabetes & Metabolism Case Reports·Ana G FerreiraJorge R Portugal
Jan 22, 2010·Clinical Nuclear Medicine·Ba D Nguyen, Michael C Roarke
Oct 22, 2015·World Journal of Clinical Cases·Amanda BaileyJon Cardinal

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