Intrathecal fentanyl prolongs sensory bupivacaine spinal block

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
H SinghA H Giesecke

Abstract

The purpose of investigation was to study the effect of intrathecal fentanyl on the onset and duration of hyperbaric bupivacaine-induced spinal block in adult male patients. Forty-three patients undergoing lower extremity or genitourinary surgery were enrolled to receive either 13.5 mg hyperbaric bupivacaine 0.75% + 0.5 ml CSF it, (Group I) or 13.5 mg hyperbaric bupivacaine 0.75% + 25 micrograms fentanyl it, (Group II) according to a randomized assessor-blind protocol. The onset and duration of sensory block were assessed by pinching the skin with forceps in the midclavicular line bilaterally every two minutes for first twenty minutes and then every five to ten minutes. Similarly, the onset and duration of motor block were assessed and graded at the same time intervals using the criteria described by Bromage. The time required for two sensory segment regression and sensory regression to L1 dermatome was 74 +/- 18 and 110 +/- 33 min vs 93 +/- 22 and 141 +/- 37 min in Groups I and II, respectively (P < 0.05). Intrathecal fentanyl did not enhance the onset of sensory or motor block, or prolong the duration of bupivacaine-induced motor spinal block. Fewer patients demanded pain relief in the fentanyl-treated group than in the contr...Continue Reading

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Citations

Sep 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Y MiwaK Fukushima
May 23, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·G M Hare, J C Ngan
May 26, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·H Vaghadia
Oct 27, 2009·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dermot O'DonnellRichard Brull
Sep 16, 2000·Journal of Pain and Symptom Management·G BennettT Yaksh
Aug 5, 1998·Acta Anaesthesiologica Scandinavica·L WestmanA Ekblom
Dec 18, 2009·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Feng-Fang TsaiLi-Kuei Chen
Oct 4, 2008·The Journal of International Medical Research·A GurbetN H Bahtiyar
Mar 28, 2002·European Journal of Anaesthesiology·J P R LoughreyJ Gardiner
Jun 24, 2000·European Journal of Anaesthesiology·D MichaloudisA Flossos
Dec 9, 1997·Anesthesia and Analgesia·S S LiuM F Mulroy

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