PMID: 7008655Feb 1, 1981Paper

Intrathecal injection of morphine for obstetric analgesia

Anesthesiology
A BarakaS Hajj

Abstract

Intrathecal injection of morphine was used to provide obstetric analgesia in 20 primiparous women in labor. When the cervix was at least 3 cm dilated, morphine, 1 or 2 mg, was injected intrathecally. In all parturients, labor pains were completely relieved after 15-60 min and analgesia lasted as long as eight to 11 hours. The analgesia was not associated with any alteration of pin-prick sensation or motor power, and there was no change in the arterial blood pressure or heart rate. All infants were delivered vaginally by use of episiotomy annd a low forceps, except two infants of mothers in the 2 mg of morphine group who needed cesarean section. During the second stage of labor, analgesia was supplemented by lidocaine, 2 per cent, using local perineal infiltration in 14 parturients and pudendal block in two parturients, and by epidural block in four parturients. Nineteen of the 20 newborns cried immediately at birth, and had Apgar scores o 7-9 at 1 min and 8-10 at 5 min. During the first 24 hours of life, the neurobehavioral responses of all newborns were scored as normal. Systemic maternal side effects such as somnolence, nausea, vomiting, and itching occurred in a high proportion of the parturients. However, in the majority of...Continue Reading

Citations

Nov 1, 1987·Irish Journal of Medical Science·E G CartonJ R McCarthy
Mar 1, 1986·Canadian Anaesthetists' Society Journal·M NaguibA Absood
Mar 1, 1986·Canadian Anaesthetists' Society Journal·D Biehl, R J Palahniuk
Oct 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M A Chaney
Aug 18, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S Siddik-SayyidA Baraka
Dec 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P Morgan
May 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·B Morgan
Jan 1, 1982·Neuroscience and Biobehavioral Reviews·I S ZagonE Zagon
Jan 1, 1985·Peptides·N BassoM De Marco
Mar 1, 1996·Journal of Clinical Anesthesia·G J GrantM I Zakowski
Aug 24, 2004·International Journal of Obstetric Anesthesia·N R ConnellyR K Parker
Jan 1, 1997·International Journal of Obstetric Anesthesia·C SibillaR Martinello
Mar 16, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nora V Bergasa
Jan 24, 2003·The New England Journal of Medicine·Holger K EltzschigWilliam R Camann
Jan 19, 2002·Regional Anesthesia and Pain Medicine·Brenda A BucklinJoy L Hawkins
Oct 1, 1994·British Journal of Obstetrics and Gynaecology·B M Morgan, M Y Kadim
Mar 22, 2003·The Journal of Pharmacology and Experimental Therapeutics·M C Holden KoNorah N Naughton
Sep 1, 1982·Postgraduate Medical Journal·P V Scott, H B Fischer
May 1, 1997·Anesthesia and Analgesia·C M ViscomiN L Pace
Mar 29, 2000·Anesthesia and Analgesia·C M PalmerD M Alves
Aug 21, 2008·Anesthesia and Analgesia·Brendan Carvalho
Apr 5, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hannah R Moser, Glenn J Giesler
Sep 10, 2003·CNS Drugs·Peter DeBalli, Terrance W Breen
Jun 24, 1998·Anesthesiology·R D'AngeloB L Raphael
Jan 29, 2003·Anesthesiology·Alain BorgeatCarlo A Schenker
Jan 1, 1993·Acta Anaesthesiologica Scandinavica·K KirnöM Elam
Feb 3, 2016·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Sarah Armstrong, Roshan Fernando
Jun 1, 1994·American Journal of Obstetrics and Gynecology·L A RustE I Nelson
Feb 5, 2008·Clinics in Liver Disease·Nora V Bergasa
Jul 1, 1987·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P HéeA Steentoft
Jan 1, 1992·International Journal of Obstetric Anesthesia·J A LuthmanJ B White
Jul 1, 1984·Surgical Neurology·C A CobbK A Smith
Feb 19, 1999·Baillière's Clinical Obstetrics and Gynaecology·D J Wilson, M J Douglas
Jan 1, 1987·Acta Anaesthesiologica Scandinavica. Supplementum·C Benedetti
Jan 1, 1984·Acta Anaesthesiologica Scandinavica. Supplementum·G Nordberg
Mar 28, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Justin Sangwook KoJae Won Joh

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