Intrathecal morphine versus epidural ropivacaine infusion for analgesia after Cesarean section: a retrospective study

JA Clinical Reports
Hiroko SuzukiKazunori Sato

Abstract

Analgesia after Cesarean delivery (CD) requires early ambulation to prevent thromboembolic disease and to facilitate baby care. We retrospectively reviewed anesthesia charts and medical records of patients who underwent CD to compare the efficacy of spinal anesthesia supplemented with intrathecal morphine hydrochloride (ITM) and combined spinal-epidural anesthesia followed by opioid-free epidural analgesia (CSEA-EDA). All subjects underwent CD at Nagaoka Chuo General Hospital between February 2012 and January 2013. Patient characteristics, time to first analgesic rescue after CD, and analgesic use after CD were examined. Incidences of postural hypotension, lower extremity numbness/weakness, postoperative nausea/vomiting (PONV), and pruritus were also examined for 48 h after CD. Average time to first analgesic use after CD (ITM 25.13 ± 16.07 h, CSEA-EDA 22.42 ± 16.27 h,p = 0.521) and cumulative probability of rescue analgesic use (p = 0.139 by log-rank test) were comparable between groups. However, average analgesic use within 24 h was lower in the ITM group (0.75 ± 1.05 times) than in the CSEA-EDA group (1.52 ± 1.72 times,p = 0.0497). Numbness or motor weakness in lower extremities only occurred in the CSEA-EDA group, and pruri...Continue Reading

References

Mar 20, 2010·Acta Anaesthesiologica Scandinavica·S M Siddik-SayyidM T Aouad

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Methods Mentioned

BETA
Cesarean section
Cesarean
PCA

Software Mentioned

XLSTAT
Excel

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