Intrathoracic extramedullary haematopoiesis manifested as a neoplastic lesion within anterior mediastinum

The Annals of Thoracic Surgery
Mario SantiniFilomena Napolitano

Abstract

Intrathoracic extramedullary hematopoiesis (EMH), the formation of apparently normal blood cells outside the confines of the bone marrow, is an uncommon but well-defined entity. It is usually associated with hematologic disorders and located in the lower paravertebral sulci or rarely in the pleura. We report a case of EMH, which presented in a patient without hematologic disorders and was manifested as an anterior mediastinal mass. The first interesting aspect of our case was that EMH occurred in a patient with normal laboratory findings and no past medical history of anemia. The second remarkable characteristic was that EMH manifested as an anterior mediastinal mass, mimicking a neoplastic lesion. Definitive diagnosis of EMH was established by a video-assisted thoracoscopic surgical biopsy. In light of this diagnosis, no further surgical procedure was carried out.

References

Oct 1, 1995·Chest·R D Yusen, M H Kollef
Sep 27, 2005·The Annals of Thoracic Surgery·Arup K GhoshLoïc Lang-Lazdunski

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Citations

Jan 29, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alfonso FiorelliMario Santini

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