Intrathoracic extramedullary hematopoiesis: report of a case in a patient with sickle-cell disease-beta-thalassemia

American Journal of Clinical Pathology
R VeraniJ L Moake

Abstract

A case of paravertebral extramedullary hematopoiesis in a patient with sickle-cell anemia-beta-thalassemia is reported. Interesting aspects in this case, including the high level of Hb F and large number of nucleated erythrocytes in the peripheral blood, are discussed. Fifty-five cases of intrathoracic extramedullary hematopoiesis have been reported. Most of these cases occurred in patients with thalassemia or hereditary spherocytosis. Extramedullary hematopoiesis should be considered in the differential diagnosis of a posterior mediastinal mass in a patient who has chronic anemia or other syndromes associated with extramedullary hematopoiesis.

Citations

Dec 1, 1992·American Journal of Hematology·J H WuR S Lan
Oct 1, 1993·Diagnostic Cytopathology·S S RaabK R Geisinger
Aug 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·A W IbrahimA Kuppa
Feb 15, 2001·The Journal of Urology·I SaisornP Leemanont
May 3, 2013·Journal of Cardiothoracic Surgery·Dmitry BobylevMarcus Krueger
Aug 1, 1987·Cancer·G S MasseyW L Marsh
Jan 1, 1984·Skeletal Radiology·G Edelstein, M Kyriakos
Jan 1, 1997·Diagnostic Cytopathology·L B LemosZ Cason

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.