PMID: 7546379Apr 1, 1995Paper

Intrathymic and extrathymic clonal deletion of T cells

Current Opinion in Immunology
J Sprent, S R Webb

Abstract

Clonal elimination accounts for self-tolerance induction in the thymus and also affects mature T cells responding to exogenous antigens in the periphery. Recent evidence on the microenvironments, cell-cell interactions and signalling requirements for clonal deletion of immature and mature T cells is discussed.

References

May 1, 1992·The Journal of Experimental Medicine·N J VasquezS M Hedrick
Jan 1, 1992·Annual Review of Immunology·J J CohenK S Sellins
Jan 1, 1992·European Journal of Immunology·K RobertsonA Mitchison
Mar 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·J H RussellP Meleedy-Rey
Mar 8, 1991·Science·B Rocha, H von Boehmer
Jan 1, 1988·Immunological Reviews·J SprentY Ron
Dec 1, 1993·The Journal of Experimental Medicine·M R AldersonD H Lynch
Mar 1, 1994·European Journal of Immunology·K M DebatinP H Krammer
Feb 1, 1993·European Journal of Immunology·A R LussowH R MacDonald
Jan 1, 1993·Annual Review of Immunology·E E SercarzK Moudgil
Jun 1, 1993·Current Opinion in Immunology·L B King, J D Ashwell
Dec 1, 1994·Immunology Today·G NúñezM González-García
Apr 1, 1994·Immunity·N J VasquezS M Hedrick
Mar 1, 1994·The Journal of Experimental Medicine·A O HueberH T He
Jan 1, 1994·Annual Review of Immunology·K Pfeffer, T W Mak
Aug 1, 1994·Immunology Today·P G Ashton-Rickardt, S Tonegawa
Oct 25, 1994·Proceedings of the National Academy of Sciences of the United States of America·J Gratiot-DeansL A Turka
Nov 1, 1994·The Journal of Experimental Medicine·T HankeT Hünig
Jun 30, 1994·Nature·S C JamesonM J Bevan
Apr 1, 1994·Current Opinion in Immunology·P H KrammerK M Debatin

❮ Previous
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Citations

Mar 29, 2002·Diabetes/metabolism Research and Reviews·Alberto Pugliese, Donatella Miceli
Jul 1, 1996·Stem Cells·F Hirayama, M Ogawa
Mar 24, 2004·Current Diabetes Reports·Kamalaveni R Prabakar, Alberto Pugliese
Feb 1, 1996·Molecular Aspects of Medicine·D J McConkeyS Orrenius
Apr 14, 2005·Seminars in Immunology·Charles D Surh, Jonathan Sprent
Jun 11, 2005·Seminars in Immunology·Li Wu, Ken Shortman
Jun 22, 1999·Journal of Neuroimmunology·R SacedónA G Zapata
Jul 1, 1997·Immunology Today·C Ardavín
Dec 14, 2002·Human Immunology·Bianca BlomHergen Spits
May 20, 1998·Research in Immunology·M G von Herrath
Dec 1, 1996·Current Opinion in Immunology·J F Miller, A Basten
Dec 1, 1996·Current Opinion in Immunology·M G von Herrath, M B Oldstone
Apr 1, 1996·Current Opinion in Immunology·A M Kruisbeek, D Amsen
Jun 1, 1997·Current Opinion in Immunology·J Sprent
Mar 11, 1998·Current Opinion in Immunology·P LuP S Linsley
Oct 18, 2003·Seminars in Immunology·Ignacio Moreno de AlboránCarlos Martínez-A
Feb 5, 2002·Microbes and Infection·Charles D Surh, Jonathan Sprent
Jun 1, 1996·Immunology and Cell Biology·S Alberti
Oct 23, 2001·Nature Immunology·H Kishimoto, J Sprent
May 26, 1998·Scandinavian Journal of Immunology·A V ReisaeterJ E Brinchmann
Mar 26, 2003·Journal of Gastroenterology and Hepatology·Soichiro UeharaYoshimura Tomita
Mar 17, 2006·The New England Journal of Medicine·Hong Jiang, Leonard Chess
Mar 19, 1996·Proceedings of the National Academy of Sciences of the United States of America·A MondinoM K Jenkins
Aug 1, 1996·The Journal of Experimental Medicine·H KishimotoJ Sprent
Jun 6, 1998·The Journal of Experimental Medicine·H KishimotoJ Sprent
Aug 22, 2000·The Journal of Experimental Medicine·C D Surh, J Sprent
May 11, 2005·The Journal of Experimental Medicine·Anne M ErcoliniElizabeth M Jaffee
Apr 21, 2010·The Journal of Experimental Medicine·Nichole M DanzlKonstantina Alexandropoulos
Jan 13, 2006·Immunology and Cell Biology·Erika CretneyThomas J Sayers
Apr 1, 1996·Immunological Reviews·P C DohertyR A Tripp
Apr 1, 1997·Immunological Reviews·J SprentS Sun
Jul 21, 1998·Annals of the New York Academy of Sciences·S Ragheb, R P Lisak
Dec 16, 1998·Molecular Pathology : MP·S J NaylerK Cooper
Dec 16, 1998·Molecular Pathology : MP·P BroussetG Delsol
Feb 28, 2002·Annual Review of Immunology·Jonathan Sprent, Charles D Surh

❮ Previous
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