PMID: 8598978Mar 1, 1996Paper

Intrauterine diagnosis of sex chromosome aneuploidy

Obstetrics and Gynecology
M G LindenA Robinson

Abstract

To provide current information on sex chromosome aneuploidies to obstetricians who encounter such diagnoses and who counsel prospective parents faced with the prenatal diagnosis of a sex chromosome aneuploidy. Unbiased information about the natural course of sex chromosome aneuploidy has become available only in the last few years. Current knowledge is based on seven prospective studies on unselected individuals with sex chromosome aneuploidy identified 20-30 years ago. All literature on sex chromosome aneuploidy was reviewed. Karyotypes specifically addressed included the following: 47,XXY, 47,XXX, 47,XYY, 45,X, 45,X/46,XX, 46,XX/47,XXX, and 46,XY/47,XXY. The international studies followed the affected subjects from birth to young adulthood. All published reports, case studies, and articles were reviewed. All prospective studies were included in the course of determining necessary information for obstetricians and prospective parents. Points addressed for each of the aneuploid karyotypes included expected phenotype, reproductive competence, developmental risks, and intervention therapies. Information about sex chromosome aneuploidy can assist obstetricians in providing accurate and comprehensive genetic counseling to parents o...Continue Reading

Citations

Jul 13, 2002·American Journal of Medical Genetics·Mary G Linden, Bruce G Bender
Dec 21, 2006·Archives of Gynecology and Obstetrics·Vorapong Phupong, Tul Sittisomwong
Jan 19, 2008·American Journal of Medical Genetics. Part a·Teresa LettieroMariacarolina Salerno
May 26, 2006·Prenatal Diagnosis·Brian L ShafferMary E Norton
Jan 30, 2015·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Liu WangQinghua Shi
Jun 11, 2014·Nature Reviews. Endocrinology·John M HutsonSamuel D Pennell
Aug 27, 2015·European Journal of Human Genetics : EJHG·Nikki C GrattonGaia Scerif
Jul 19, 2017·Human Fertility : Journal of the British Fertility Society·Parnaz Borjian BoroujeniAnahita Mohseni Meybodi
Sep 12, 2017·The Journal of Obstetrics and Gynaecology Research·Po Lam SoHoi Yin Mary Tang
Jul 13, 2002·American Journal of Medical Genetics·Mary G LindenArthur Robinson
Jul 2, 2004·Obstetrics and Gynecology·Gábor MezeiZoltán Papp
Jun 5, 2003·American Journal of Medical Genetics. Part a·Mathias B Forrester, Ruth D Merz
Jul 2, 2009·European Journal of Human Genetics : EJHG·Maarten OtterLeopold M G Curfs
Feb 16, 2012·Journal of Developmental and Behavioral Pediatrics : JDBP·Nicole R TartagliaRichard Boada
Jun 5, 2001·Genetics in Medicine : Official Journal of the American College of Medical Genetics·B G BenderR J Harmon
Apr 17, 1999·American Journal of Medical Genetics·B G BenderA Robinson
Oct 14, 2005·American Journal of Medical Genetics. Part a·E P M CorssmitE Fliers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.