Intrauterine Growth Restricted Rats Exercised at Pregnancy: Maternal-Fetal Repercussions

Reproductive Sciences
S B CorvinoDébora C Damasceno

Abstract

To evaluate the effect of swimming in pregnant rats born with intrauterine growth restriction (IUGR) and their offspring, IUGR rats were obtained using the streptozotocin-induced severe diabetic (SD) rats. In this study, the nondiabetic parental generation presented 10 rats and diabetic parental generation presented 116 rats. Of these, the mated nondiabetic female rats were 10 and the number of diabetic rats was 45. In relation to term pregnancy, there were 10 animals in the nondiabetic group and 15 rats in the diabetic group. In the offspring of SD rats (IUGR group), 43 females were classified as small for pregnancy age, 19 rats were classified as appropriate for pregnancy age, and 0 female was classified as large for pregnancy age. The nondiabetic and SD pregnant rats generated offspring with appropriate (control [C]) and small (IUGR) weight for pregnancy age, respectively. At adult life, the C group was maintained as nonexercised C group and IUGR rats were distributed into 2 subgroups, namely, nonexercised (IUGR) and exercised (IUGRex). The rate of mated rats in the IUGR group was reduced compared to the C group. During pregnancy, the IUGR rats presented hyperinsulinemia, impaired reproductive outcomes, decreased body weight...Continue Reading

References

Oct 1, 1977·British Journal of Obstetrics and Gynaecology·F A Van AsscheM Verjans
Nov 1, 1992·Diabetes Care·J T Devlin
Dec 1, 1991·American Journal of Obstetrics and Gynecology·P M CatalanoE A Sims
Apr 1, 1997·Acta Physiologica Scandinavica·A G NieuwenhuizenT R Koiter
Nov 30, 1998·BMJ : British Medical Journal·A LucasT J Cole
Apr 1, 1999·Journal of Hypertension·T J RoseboomO P Bleker
Oct 28, 1999·The American Journal of Clinical Nutrition·A C RavelliO P Bleker
Jul 21, 2000·The Journal of Clinical Investigation·J E Pessin, A R Saltiel
Jan 26, 2002·British Medical Bulletin·C N Hales, D J Barker
Jan 29, 2002·Diabetes·Frédérique BéringueMichel Polak
Dec 28, 2002·Diabetes·Alexandra E ButlerPeter C Butler
Jan 30, 2004·Nature·Susan E Ozanne, C Nicholas Hales
Jan 27, 2005·American Journal of Obstetrics and Gynecology·Henry L GalanTimothy R H Regnault
Feb 3, 2005·American Journal of Physiology. Endocrinology and Metabolism·Margarita Teran-GarciaClaude Bouchard
Aug 25, 2005·Trends in Endocrinology and Metabolism : TEM·Rebecca Simmons
Aug 25, 2005·The International Journal of Biochemistry & Cell Biology·L Aerts, F A Van Assche
Nov 3, 2005·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Haim BassanShaul Harel
Jun 20, 2006·Physiology & Behavior·D S Fernandez-Twinn, S E Ozanne
Sep 27, 2007·American Journal of Physiology. Endocrinology and Metabolism·Sean W LimesandWilliam W Hay
Apr 30, 2009·Reproductive Biomedicine Online·Maricelma da Silva Soares de SouzaDébora Cristina Damasceno
Dec 25, 2009·Reproductive Biomedicine Online·G T VolpatoI Mp Calderon
Sep 16, 2010·Annals of the New York Academy of Sciences·Christina Kanaka-Gantenbein
Dec 15, 2010·International Journal of Women's Health·Catherine Kim
Jun 15, 2011·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·D C DamascenoI M P Calderon
Jul 4, 2013·Clinical Obstetrics and Gynecology·Kathryn L Gatford, Rebecca A Simmons

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Citations

Sep 9, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·S B CorvinoD C Damasceno
Apr 4, 2017·Acta Physiologica·J Denham
Apr 20, 2017·Anais Da Academia Brasileira De Ciências·Silvana B CorvinoGustavo T Volpato
Dec 18, 2020·Anais Da Academia Brasileira De Ciências·Aline O NettoDÉbora C Damasceno
Sep 27, 2018·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·A O NettoD C Damasceno

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Methods Mentioned

BETA
SGA

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