Intravascular Large B-Cell Lymphoma Presenting with Diffuse Gallbladder Wall Thickening: A Case Report and Literature Review

Case Reports in Radiology
Sayf Al-KatibFarnoosh Sokhandon

Abstract

Intravascular large B-cell lymphoma is a rare subtype of extranodal diffuse B-cell lymphoma characterized by proliferation of neoplastic cells within the lumen of small and medium sized vessels. Clinical and imaging findings are nebulous as the intravascular subtype of lymphoma can involve a multitude of organs. Involvement of the gallbladder is extremely uncommon, and imaging findings can be easily confused for more prevalent pathologies. We report a case of intravascular large B-cell lymphoma in an 83-year-old male and review clinical presentation and imaging findings on CT, ultrasound, hepatobiliary iminodiacetic acid (HIDA) scan, and MRI. It is important for the radiologist to know about this disease as the imaging findings are atypical of other types of lymphoma, and this may lead to a delay in diagnosis and treatment.

References

Jul 1, 1997·Journal of Magnetic Resonance Imaging : JMRI·K YoshimitsuK Masuda
Jan 24, 2007·AJR. American Journal of Roentgenology·Adriaan C van Breda VriesmanJulien B C M Puylaert
Sep 1, 2009·The Lancet Oncology·Kazuyuki ShimadaShigeo Nakamura

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Citations

Oct 28, 2019·BMJ Open Gastroenterology·Anusha Shirwaikar ThomasEamonn Quigley
Dec 13, 2019·Case Reports in Hematology·Pier Paolo PiccalugaLuigi Bolondi

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Methods Mentioned

BETA
Flow cytometry
biopsy

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