Intravascular Lithotripsy for Treatment of Calcified, Stenotic Iliac Arteries: A Cohort Analysis From the Disrupt PAD III Study.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
Ehrin J ArmstrongNelson L Bernardo

Abstract

The presence of calcification in the iliac arteries is associated with decreased procedural success and increased complication risk during endovascular intervention. The objective of this study was to evaluate the safety and efficacy of peripheral intravascular lithotripsy (IVL) during endovascular treatment of iliac arterial peripheral artery disease (PAD). The Disrupt PAD III Observational Study is a prospective, non-randomized, multi-center single-arm study to assess the 'real-world' safety and effectiveness of the Shockwave Peripheral IVL System for the treatment of de novo calcified lesions in the peripheral arteries, with a goal of treating 1500 patients. This is an analysis of consecutive patients enrolled for treatment of an iliac artery, a specified sub-group, with at least moderate calcification and a minimum length of 20 mm. Between December 2017 and July 2019, 118 patients with a total of 200 lesions were enrolled across 20 sites. 101 patients were treated primarily for claudication or critical limb ischemia, while 17 patients were treated to optimize the iliac vasculature for large-bore access. All 118 patients had successful IVL catheter delivery. The average reference vessel diameter was 7.3 mm ± 1.9 mm, with an ...Continue Reading

Citations

Jul 3, 2020·The Journal of Cardiovascular Surgery·Rafael D MalgorDonald L Jacobs
Mar 6, 2021·Current Cardiology Reports·E Hope WeisslerRajesh V Swaminathan
Feb 26, 2021·Progress in Cardiovascular Diseases·Isma N Javed, Beau M Hawkins
May 26, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Gaetano Di Palma, Bernardo Cortese
Jul 1, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Keyvan Karimi GalougahiZiad A Ali
Aug 13, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·George AdamsEhrin J Armstrong

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