PMID: 9163885May 1, 1997Paper

Intravascular malignant T-cell lymphoma (malignant angioendotheliomatosis) in a cat

Veterinary Pathology
J M LapointeP F Moore

Abstract

A 7-year-old spayed female Siamese cat was presented with a 7-day history of ataxia, circling to the right, and involuntary micturition and defecation. Cerebrospinal fluid analysis showed increased protein content and relative eosinophilia. At necropsy, there was flattening of the cerebral cortical gyri of the right frontal and parietal lobes, and both kidneys had multiple wedge-shaped cortical indentations. Histologically, the cerebral cortex contained several extensive malacic foci, and the kidneys had multifocal parenchymal degeneration and atrophy. There was multifocal partial to complete thrombosis of renal interlobar arteries and of the right middle cerebral artery and meningeal branches; these thrombi contained large anaplastic round cells, which often invaded the arterial wall. Many smaller vessels within the kidneys and brain were occluded with clusters of similar cells, without thrombosis or vascular wall invasion. The neoplastic round cells had immunohistochemical staining properties of T lymphocytes.

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Citations

Jan 13, 2009·Journal of Feline Medicine and Surgery·Helge LinzmannRobert Klopfleisch
Sep 20, 2002·The Journal of Small Animal Practice·V R BarrsA Kipar
Jun 21, 2002·Veterinary Clinical Pathology·Catherine E. Thorn, Isabelle Aubert
Jan 21, 2012·Veterinary Clinical Pathology·Laura V LaneWilliam Vernau
Jan 29, 2003·Journal of the American Animal Hospital Association·William W BushTom J Van Winkle
Jan 31, 2012·The Veterinary Clinics of North America. Small Animal Practice·Michael O Childress
Sep 8, 2006·Journal of Veterinary Internal Medicine·S L RaidalS R Raidal
May 6, 2016·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Amy E SchkeeperRichard Weiss
Oct 1, 2016·The Veterinary Journal·Maria Teresa MandaraPietro Calò
Nov 30, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·M HenrichM Reinacher
May 13, 2005·Australian Veterinary Journal·L Ridge, G Swinney
Mar 8, 2017·Primate Biology·Karen LampeKerstin Mätz-Rensing
Jan 5, 2002·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·M KentA S Tidwell

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