Intravascular Ultrasound Validation of Contemporary Angiographic Scores Evaluating the Severity of Calcification in Peripheral Arteries

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
Da YinWilliam A Gray

Abstract

To validate 3 angiographic scoring systems for peripheral artery calcification using intravascular ultrasound (IVUS) as the gold standard. The study employed preprocedure angiography and IVUS data from 47 patients (median age 72 years; 34 men) in the 55-patient JetStream G3 Calcium Study ( ClinicalTrials.gov identifier NCT01273623) to validate the 3 angiographic scoring systems [Peripheral Academic Research Consortium (PARC), Peripheral Arterial Calcium Scoring System (PACSS), and the DEFINITIVE Ca++ trial]. Preprocedure angiograms were analyzed using conventional quantitative vessel analysis software in 2 orthogonal views. Calcium length was evaluated by markers placed beside the artery during the procedure; calcium deposit(s) were assessed as being on one or both sides of the vessel wall. The 3 calcium scoring systems used these 2 basic angiographic elements to evaluate calcium severity. Based on these criteria, calcium severity varied from none to focal, mild, moderate, or severe in PARC; grade 0 to 4 in PACSS; and none, moderate, or severe in the DEFINITIVE Ca++ system. Calcium location on IVUS was classified as superficial, deep, or mixed. Lesion length was the segment between the most normal looking proximal and distal re...Continue Reading

Associated Clinical Trials

References

Dec 6, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Matthew A AllisonC Michael Wright
Feb 8, 2008·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Vikram S KashyapKenneth Ouriel
May 17, 2008·Journal of the American College of Cardiology·Raul J GuzmanXiao Qin
Jun 4, 2008·Circulation·Linda L Demer, Yin Tintut
May 30, 2009·Journal of the American Society of Nephrology : JASN·Masahide MizobuchiEduardo Slatopolsky
Mar 4, 2011·Atherosclerosis·Fanny HerissonYann Gouëffic
Jan 10, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·David RobertsUNKNOWN DEFINITIVE Ca⁺⁺ Investigators
Jan 10, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Krishna J Rocha-SinghMichael R Jaff
Feb 18, 2014·Journal of the American College of Cardiology·Mahesh V MadhavanPhilippe Généreux
May 9, 2014·Cardiovascular and Interventional Radiology·F FanelliF M Salvatori
Mar 7, 2015·Journal of the American College of Cardiology·W Schuyler JonesLesley H Curtis
May 20, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Akiko MaeharaWilliam A Gray
Aug 5, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·UNKNOWN TASC Steering CommitteeLars Norgren
Aug 8, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Gunnar TepeThomas Zeller

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Citations

Apr 5, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Adam MazurekPiotr Musialek
Apr 20, 2021·Journal of Medical Economics·Elizabeth A MagnusonUNKNOWN LIBERTY 360° Trial Investigators
Jun 4, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Krishna J Rocha-SinghUNKNOWN REALITY Investigators
Apr 27, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Hiroyuki JinnouchiAloke V Finn

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Methods Mentioned

BETA
amputation

Clinical Trials Mentioned

NCT01273623

Software Mentioned

QCA
echoPlaque
SPSS
PACSS
QAngio XA
- CMS

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