May 1, 1977

Intravenous bolus of 125I labeled meglumine diatrizoate. Early extravascular distribution

Acta Radiologica: Diagnosis
P B Dean, M Kormano

Abstract

A mixture of 125I labeled meglumine diatrizoate and 131I labeled human serum albumin was injected into the femoral vein of 26 anesthetized male rats. Measurements of the activities in cardiac blood and in different tissues of the lower extremity and in the testis were performed at time intervals ranging from 5 s to 5 min after injection. The determination of tissue uptake and distribution volumes of diatrizoate showed widely differing accumulation of contrast medium. Over 50 per cent of the intravenous bolus of diatrizoate was extravascular at 40 s.

Mentioned in this Paper

Benign Neoplasm of Testis
Serum Albumin, Radio-Iodinated
Neoplasm of Uncertain or Unknown Behavior of Testis
Intravenous Injections
August Rats
ALB
Uptake
Albumin Human, USP
Intravenous Bolus
Human Serum Albumin [EPC]

About this Paper

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