Intravenous immunoglobulin therapy for diabetic amyotrophy

Internal Medicine
T OgawaI Nakano

Abstract

A 49-year-old woman with diabetes mellitus developed progressive weakness and atrophy of both thighs rendering her wheelchair-bound within two months. The neurological findings and electrophysiological test results were compatible with diabetic amyotrophy (DA). Immediately after intravenous immunoglobulin (IVIg) therapy (20 g x 3 days), she became able to walk with a cane. After the next course of the therapy, she could walk without assistance. This dramatic effect of IVIg therapy together with the recent observation of vasculitic neuropathy in DA indicates an inflammatory process in this condition, and gives support to this treatment for DA.

Citations

Mar 20, 2003·Current Diabetes Reports·Rayaz A Malik
Jan 1, 2009·BMJ Case Reports·Yuichi KawagashiraGen Sobue
Jul 20, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·Y KawagashiraG Sobue
May 27, 2004·Diabetes Care·Andrew J M BoultonJay M Sosenko
Jan 8, 2004·Endocrine Journal·Tsukasa MoriiSeiki Ito

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