Intravenous ketogenic diet therapy for treatment of the acute stage of super-refractory status epilepticus in a pediatric patient

Pediatric Neurology
Jainn-Jim LinCHEESE Study Group

Abstract

A ketogenic diet has been used successfully to treat intractable epilepsy. However, the role of early intravenous initiation of ketogenic diet in the acute phase of super-refractory status epilepticus is not well-described. An intravenous ketogenic diet was administered to a boy with super-refractory status epilepticus. At 24 hours after intravenous ketogenic diet, moderate ketosis appeared, and thiamylal was successfully weaned at 70 hours after admission. An intravenous ketogenic regimen led to subsequent ketosis and seizure control in a child with super-refractory status epilepticus. Early induction of ketosis may be a novel strategy to effectively treat super-refractory status epilepticus. Although there are few data regarding the early use of intravenous ketogenic diet in the treatment of super-refractory status epilepticus, it may be considered an alternative option.

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Citations

Mar 29, 2018·Epilepsia Open·Anastasia DresslerMartha Feucht
Jul 17, 2018·Clinical Pediatrics·Amanda R DahlRobin M Lloyd
Aug 15, 2018·Archives of Disease in Childhood·Petros Fessas, Amedine Duret
Jul 18, 2019·Developmental Medicine and Child Neurology·Elles van der LouwUNKNOWN Review Group
Mar 7, 2020·Epilepsia Open·Sherif Hanafy MahmoudJessica Buhler
Sep 6, 2020·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Vincent Zimmern, Christian Korff
Nov 7, 2020·Seminars in Neurology·Tanya J W McDonald, Mackenzie C Cervenka
Mar 16, 2021·Epilepsy Currents·Juan G OchoaDavid G Vossler
Jul 10, 2020·Biomedical Journal·Kuang-Lin LinHuei-Shyong Wang

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