Intravenous mirtazapine is safe and effective in the treatment of depressed inpatients

Neuropsychobiology
M MühlbacherC Stuppaeck

Abstract

Mirtazapine is a third-generation antidepressant with a dual mode of action. The oral administration has been shown to be effective and safe in the treatment of depressed patients. In this multicenter naturalistic study, we assessed the safety, tolerability, and therapeutic efficacy of intravenously administered mirtazapine in 80 moderately to severely depressed inpatients during a treatment period of 14 days. We found a significant decrease of the Hamilton Depression Rating Scale total score compared to baseline. Side effects were mild and transient. Our data indicate that intravenous mirtazapine is an effective, safe and well-tolerated treatment for depressed inpatients.

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Citations

Dec 22, 2012·The British Journal of Psychiatry : the Journal of Mental Science·Renee RomeoSube Banerjee
Mar 7, 2009·Journal of Psychopharmacology·A AttardD Taylor
Nov 8, 2014·The Cochrane Database of Systematic Reviews·Maria KleinstäuberMichael J Lambert

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