Intravenous paracetamol infusion versus intramuscular tramadol as an intrapartum labor analgesic

Journal of Obstetrics and Gynaecology of India
Meenakshi LallarSurabhi Katyal

Abstract

To compare intravenous paracetamol and intramuscular tramadol as labor analgesics. This prospective-randomized study conducted in 200 primigravidae in active labor, distributed into two groups of 100 women each with one receiving intravenous 1,000 mg Paracetamol and other 100 mg intramuscular tramadol. Pain intensity is recorded by McGills scale before, one and 3 h after drug administration. Perinatal outcome is recorded. No difference in pain intensity is seen before drug administration. After 1 h of drug administration, in paracetamol group, 4 % women had horrible pain, and 29 % had distressing pain, while in tramadol group, 30 % women had horrible pain, and 60 % had distressing pain. After 3 h of drug administration, in paracetamol group, 26 % had distressing pain, while in tramadol group, 51 % women had horrible pain, and 35 % had distressing pain. Labor duration in paracetamol and tramadol group was 4.3 and 5.9 h, respectively. In paracetamol group, nausea is seen in 2.2 % and vomiting in 1.1 %, while in tramadol group, nausea is seen in 6.4 % and vomiting in 4.3 %. Intravenous paracetamol is more effective labor analgesic with fewer maternal adverse effects and shortens labor as compared to intramuscular tramadol.

References

Sep 9, 2010·The Cochrane Database of Systematic Reviews·Roz UllmanTherese Dowswell
Dec 31, 2010·Indian Journal of Anaesthesia·Sunil T Pandya
Apr 17, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ahmed E H ElbohotyKarim H I Abd-El-Maeboud
Jun 28, 2014·Nigerian Medical Journal : Journal of the Nigeria Medical Association·Mohammad-Hasan AbdollahiMohammad Naghavi-Behzad

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Citations

Jun 6, 2018·The Cochrane Database of Systematic Reviews·Lesley A SmithAnna Cuthbert
Apr 28, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohamed Elsibai AnterAhmed Mohamed Nofal

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