Intravenous Paracetamol Overdose: A Pediatric Case Report

Pediatric Emergency Care
Nagehan AslanSevcan Bilen

Abstract

Paracetamol is a common antipyretic often used to treat children with fever and pain. With the increasing administration of intravenous (IV) paracetamol, there will be the associated risk of medication dosing errors. We report a case of IV paracetamol overdose in a child with fever during hospital admission. A IV paracetamol dosing error occurred, with delayed recognition resulting in transient hepatotoxicity, with a peak alanine transaminase of 1946 IU/L and aspartate transaminase of 1633 IU/L.

References

Aug 1, 1991·British Journal of Clinical Pharmacology·A Penna, N Buchanan
Sep 15, 1999·The Journal of Pediatrics·B J AndersonR Aicken
Jan 24, 2007·QJM : Monthly Journal of the Association of Physicians·C BeerS H L Thomas
Apr 2, 2009·Paediatric Anaesthesia·Elaine M Wilson-Smith, Neil S Morton
Dec 4, 2010·Archives of Disease in Childhood·Richard M BeringerPeter A Stoddart
Nov 26, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Ingrid BerlingGeoffrey K Isbister
Jan 25, 2012·Pediatrics·Richard C Dart, Barry H Rumack

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Citations

Jan 4, 2021·European Journal of Clinical Pharmacology·Cristian LocciRoberto Antonucci

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