Intravenous tenoxicam reduces uterine cramps after Cesarean delivery

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Yu-Chen HuangWei-Zen Sun

Abstract

Postpartum uterine contraction pain is a common phenomenon after Cesarean delivery. We investigated the effectiveness of tenoxicam in reducing uterine contraction pain. We enrolled 120 consecutive non-breastfeeding women who were scheduled for elective Cesarean delivery. After the administration of spinal anesthesia with bupivacaine and intrathecal morphine 0.15 mg injection, the patients were randomly divided into two groups. Group I received placebo (normal saline) iv injection, and Group II received tenoxicam 40 mg iv injection after clamping the umbilical cord. Verbal analogue scale of wound pain and uterine contraction pain were recorded at two, four, eight,16, and 24 hr after Cesarean delivery. There was no significant difference in wound pain scores between the two groups (all scores < or =3). However, the tenoxicam group had significant lower uterine contraction pain scores and required less supplemental meperidine medication than did the placebo group (8.5% vs 41.4%, P <0.05). The incidences of nausea or vomiting, pruritus, and bleeding were not significantly different between groups. Intravenous tenoxicam 40 mg significantly reduced the intensity of uterine cramps in patients undergoing Cesarean delivery without incre...Continue Reading

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Citations

Oct 11, 2011·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Ming-Cheng ChangWei-Zen Sun
Apr 27, 2007·International Journal of Obstetric Anesthesia·M R El-TahanM K Matter
Aug 20, 2015·AAPS PharmSciTech·Shishu GoindiAtin Kalra
Aug 1, 2015·BMC Veterinary Research·M SchneiderF Woehrlé
Nov 18, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nuray BozkurtKutay Biberoglu
Jun 1, 2006·Current Opinion in Anaesthesiology·Patricia Lavand'homme
Apr 6, 2013·Anesthesia and Analgesia·Melanie Bloor, Michael Paech
May 12, 2021·Journal of Clinical Anesthesia·Vaniely Kaliny Pinheiro de QueirozGuilherme Antonio Moreira de Barros

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