Intraventricular Glioblastomas

World Neurosurgery
Atef Ben NsirHafedh Jemel

Abstract

Although glioblastoma is the most common primary brain tumor, primary intraventricular locations are extremely rare; only 21 cases have been reported to date. A retrospectively acquired database of all intracranial glioblastomas treated in 2 different neurosurgical departments during the last 10 years was queried. Patients with histologically proven intraventricular glioblastomas were included in the study. Eight patients were identified as having a histologically confirmed intraventricular glioblastoma. Patient age at diagnosis ranged from 6 to 74 years (mean 29.6 years) and the male/female ratio was 5:3. Increased intracranial pressure due to hydrocephalus was the main cause of the clinical manifestations. The tumor was located within the lateral ventricle in 6 cases and the anterior third ventricle in 2 others. Gross total tumor excision was achieved in 3 patients, whereas the surgical resection was subtotal in 4 cases and a surgical biopsy was performed in 1 patient. Postoperative adjuvant therapies were administered in 5 patients. Median survival time was 32.1 months, and 3 patients were alive at the end of study. All of them had isocitrate dehydrogenase-mutated tumors. Intraventricular glioblastoma is extremely rare and c...Continue Reading

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Oct 8, 2016·Neuroimaging Clinics of North America·Lazaro D CausilMauricio Castillo
Jan 10, 2018·Pediatric Neurosurgery·Mustafa Kemal DemirMelisa Aslan
Aug 13, 2021·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Kosuke TakigawaMasahiro Mizoguchi

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