Intraventricular hemorrhage in asphyxiated newborns treated with hypothermia: a look into incidence, timing and risk factors

BMC Pediatrics
Ghalia Al YazidiP Wintermark

Abstract

Intraventricular hemorrhage (IVH) is uncommon in term newborns. Asphyxia and hypothermia have been mentioned separately as possible risk factors of IVH, since they might cause fluctuations of cerebral blood flow. The aim of this study was to assess the incidence, the timing, and the risk factors of intraventricular hemorrhage (IVH) in term asphyxiated newborns treated with hypothermia. We conducted a prospective cohort study of all term asphyxiated newborns treated with hypothermia from August 2008 to June 2013. The presence or not of IVH was assessed using brain magnetic resonance imaging (MRI) performed after the hypothermia treatment was completed or using head ultrasound during the hypothermia treatment. For these newborns, to determine the timing of IVH, we retrospectively reviewed if they had other brain imaging studies performed during their neonatal hospitalization stay. In addition, we compared their general characteristics with those not developing IVH. One hundred and sixty asphyxiated newborns met the criteria for hypothermia. Fifteen of these newborns developed IVH, leading to an estimate of 9% (95% CI: 5.3-15.0%) of IVH in this population of newborns. Fifty-three percent had hemorrhage limited to the choroid plexu...Continue Reading

References

Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·T HayashiT Hashimoto
Dec 1, 1982·Archives of Neurology·M S ScherT R Thompson
Dec 4, 1998·Stroke; a Journal of Cerebral Circulation·S SchwabW Hacke
Jan 9, 2003·Clinics in Perinatology·Abbot R Laptook, Ron J T Corbett
Jul 3, 2003·Annals of Neurology·Yvonne W WuDonna M Ferriero
Mar 30, 2005·Lancet·Jennifer BryceUNKNOWN WHO Child Health Epidemiology Reference Group
Oct 14, 2005·The New England Journal of Medicine·Seetha ShankaranUNKNOWN National Institute of Child Health and Human Development Neonatal Research Network
Mar 18, 2006·Neuroimaging Clinics of North America·A J Barkovich
Oct 3, 2009·The New England Journal of Medicine·Denis V AzzopardiUNKNOWN TOBY Study Group
Jun 18, 2010·Early Human Development·Jennifer J KurinczukNadia Badawi
Oct 8, 2011·AJNR. American Journal of Neuroradiology·P WintermarkS K Warfield
Jun 1, 2012·The New England Journal of Medicine·Seetha ShankaranUNKNOWN Eunice Kennedy Shriver NICHD Neonatal Research Network
Mar 16, 2013·AJNR. American Journal of Neuroradiology·A N MassaroC Limperopoulos

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Citations

Oct 16, 2016·The Journal of Pediatrics·Regan E GiesingerPatrick J McNamara
Dec 13, 2017·Perfusion·Katherine CashenUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Resear
Aug 4, 2018·Pediatric Research·Philip T LevyUNKNOWN European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE)
Dec 24, 2018·Acta Obstetricia Et Gynecologica Scandinavica·Katarina ÅbergCecilia Ekéus
Feb 13, 2018·Seminars in Fetal & Neonatal Medicine·Janet S Soul
Aug 22, 2021·Seminars in Fetal & Neonatal Medicine·A G Sandoval KaramianUNKNOWN Newborn Brain Society Guidelines and Publications Committee

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Methods Mentioned

BETA
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