Intravitreal amikacin in the treatment of bacterial endophthalmitis

Archives of Ophthalmology
J H TalamoK R Kenyon

Abstract

Intravitreal administration of broad-spectrum antibiotics is a widely accepted component of initial therapy for bacterial endophthalmitis. Four cases of culture-proved bacterial endophthalmitis are reported to demonstrate the safety of intravitreal administration of amikacin sulfate in conjunction with cephalosporins in patients. The benefits of using amikacin rather than gentamicin sulfate in intravitreal drug therapy are discussed, and a wider role for amikacin as the aminoglycoside of choice for initial intravitreal injection in presumed bacterial endophthalmitis is suggested.

Citations

Jun 15, 1993·American Journal of Ophthalmology·B A MandellS Gardner
Dec 10, 1999·Survey of Ophthalmology·R A Mittra, W F Mieler
Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·B S OumK W Wong
Apr 1, 1987·Ophthalmology·J C AffeldtG D Jarus
Feb 11, 2015·Journal of Ophthalmic Inflammation and Infection·Medikonda RadhikaHarry W Flynn
Jan 23, 2003·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·David L VollmerThomas M Parkinson
Dec 23, 1998·Survey of Ophthalmology·M S KresloffM A Zarbin

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