Intravitreal bevacizumab for extrafoveal choroidal neovascularization after ocular trauma

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Umberto De BenedettoPierluigi Iacono

Abstract

To describe two cases of extrafoveal choroidal neovascularization (CNV) after ocular trauma successfully treated with intravitreal bevacizumab injection. A 41-year-old man presented for progressive visual impairment in the left eye (LE). The patient had a positive history for pseudoxanthoma elasticum and suffered a blunt trauma in the LE 1 year before. Best-corrected visual acuity (BCVA) in the affected eye was 20/100. Fundus examination of the LE revealed angioid streaks and a choroidal rupture with retinal hemorrhages. Fluorescein angiography (FA) revealed an extrafoveal CNV and optical coherence tomography (OCT) findings demonstrated the presence of intraretinal fluid extending to the fovea. The second patient was a 61-year-old man complaining of blurred vision in the LE. Fundus examination of the LE revealed retinal pigment epithelium (RPE) changes, while FA showed the presence of an extrafoveal CNV close to the area of RPE attenuation. Intraretinal fluid extending to the fovea was detectable on OCT examination. An intravitreal injection of bevacizumab was proposed in both cases. In the first patient, treatment with one intravitreal bevacizumab injection was successful in contrasting CNV activity, as OCT findings showed a r...Continue Reading

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Citations

Nov 12, 2013·American Journal of Ophthalmology·Maurizio Battaglia ParodiFrancesco Bandello
Sep 30, 2015·Journal of Ophthalmology·Vikas TahSaruban Pasu
Oct 4, 2013·International Ophthalmology Clinics·Mrinali M PatelDean Eliott
Feb 7, 2019·Case Reports in Ophthalmological Medicine·Massimo LorussoTommaso Micelli Ferrari
Feb 6, 2021·Survey of Ophthalmology·Marco LupidiCarlo Cagini

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