Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion

The British Journal of Ophthalmology
Thomas C KreutzerSiegfried G Priglinger

Abstract

To evaluate the effect of intravitreal bevacizumab (Avastin) injections on visual acuity (VA) and foveal retinal thickness in patients with macular oedema secondary to branch retinal vein occlusion. A prospective, non-comparative, consecutive, interventional case series of 34 patients. Patients received repeated intravitreal injections of 1.25 mg bevacizumab. Main outcome measures were VA (Snellen charts and ETDRS) and retinal thickness (optical coherence tomography measurements) in a follow-up period of 6 months. Patients presented at a mean age of 69 years (range 44-86). Mean duration of symptoms was 40 weeks (range 1-300). Mean (SD) VA at baseline was 0.79 (0.39) logMAR, improving to 0.51 (0.34) logMAR at 6 months (p = 0.009). Mean number of letters on the ETDRS chart at baseline was 45.3 (19.0), improving to 60.6 (19.9) at 6 months (p = 0.003). Mean (SD) retinal thickness at baseline was 474 (120) microm, declining to 316 (41) microm at 6 months. Intravitreal injection of 1.25 mg bevacizumb appears to be an effective treatment option for branch retinal vein occlusion.

Citations

Jun 12, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Eun Jee ChungHyoung Jun Koh
Aug 19, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Juliane RieseHeinrich Gerding
Aug 13, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gesine B JaisslePeter Szurman
Jul 28, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alexandra E HoehStefan Dithmar
Feb 26, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yeo Jue ByunHyoung Jun Koh
Feb 22, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gesine B JaissleUNKNOWN Retinal Vein Occlusion Study Group
Aug 30, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sibylle WinterhalterAntonia M Joussen
Nov 19, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Masafumi OtaNagahisa Yoshimura
Feb 15, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alireza RamezaniMehdi Yaseri
Apr 28, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Taygan Yilmaz, Miguel Cordero-Coma
Dec 31, 2010·Japanese Journal of Ophthalmology·Masafumi OtaNagahisa Yoshimura
Dec 21, 2011·Japanese Journal of Ophthalmology·Narihisa HanadaMitsuhiro Imasawa
Mar 30, 2013·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Dan ZhuJost B Jonas
Nov 12, 2013·The British Journal of Ophthalmology·Taiichi HikichiShoko Shioya
Oct 1, 2008·BMC Ophthalmology·Mathias AbeggJohannes Fleischhauer
May 5, 2009·Ocular Immunology and Inflammation·Andrew J Barkmeier, Levent Akduman
Apr 19, 2012·Current Eye Research·Anna Cardiakidis MyersVesna Ponjavic
Feb 3, 2011·Annals of Medicine·Kati Kinnunen, Seppo Ylä-Herttuala
May 24, 2011·Survey of Ophthalmology·Justis P Ehlers, Sharon Fekrat
May 31, 2011·American Journal of Ophthalmology·Christoph EhlkenGottfried Martin
Oct 31, 2009·American Journal of Ophthalmology·John J WroblewskiChristine R Gonzales
May 9, 2009·Survey of Ophthalmology·Jonathan B Gunther, Michael M Altaweel
May 24, 2008·Acta Ophthalmologica·Peep V AlgvereStefan Seregard
May 12, 2009·Clinical & Experimental Ophthalmology·Atsushi SakamotoNagahisa Yoshimura
Feb 13, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C ChiquetC Creuzot-Garcher
Jun 6, 2009·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Amir Ali AhmadiDavid A L Maberley
Nov 11, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M Battaglia ParodiF Bandello
Nov 1, 2013·Seminars in Ophthalmology·Irini P ChatziralliMarilita M Moschos
Sep 4, 2014·The British Journal of Ophthalmology·Masahiko Shimura, Kanako Yasuda

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.