Intravitreal dexamethasone implant for cystoid macular edema and inflammation after scleral buckling

European Journal of Ophthalmology
Vincenza BonfiglioTeresio Avitabile

Abstract

Cystoid macular edema may occur following scleral buckling and therefore deteriorate the visual outcome. Inflammation may be the major causative factor in the development of postoperative cystoid macular edema. This case demonstrates the effectiveness of a dexamethasone implant as a treatment after the onset of choroidal inflammation and cystoid macular edema 6 months following scleral buckling and having visual acuity restored. A 59-year-old phakic woman treated with scleral buckling for macula-off retinal detachment presented 2 months after surgery with cystoid macular edema with choroidal inflammation. Optical coherence tomography and fluorescein angiography were performed. From the time of the diagnosis, the patient's condition had been nonresponsive to medical therapy and only partially responsive to sub-Tenon triamcinolone acetonide. An intravitreal implant with a sustained release of 0.7 mg dexamethasone was implanted. Following an intravitreal injection with a dexamethasone implant, the macular edema subsided completely and optical coherence tomography showed decreased foveal thickness from 510 μm to 220 μm. Choroidal fluorescein leakage disappeared. Best-corrected visual acuity improved from 0.70 to 0.20 logMAR, a cond...Continue Reading

References

Feb 5, 2008·American Journal of Ophthalmology·Ryan M RichJanet L Davis
Mar 10, 2009·American Journal of Ophthalmology·George A WilliamsUNKNOWN Dexamethasone DDS Phase II Study Group

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Citations

Dec 21, 2019·Clinical & Experimental Ophthalmology·Adrian T FungPaul Beaumont
Mar 17, 2020·European Journal of Ophthalmology·Michele CoppolaFrancesco Bandello
Aug 21, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Miguel A BusquetsTailun Zhao

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