INTRAVITREAL DEXAMETHASONE IMPLANT MIGRATION INTO THE ANTERIOR CHAMBER: A Multicenter Study From the Pan-American Collaborative Retina Study Group.

Retina
Mariana Batista GonçalvesPan-American Collaborative Retina Study Group

Abstract

To establish the prevalence and risk factors for intravitreal dexamethasone implant migration into the anterior chamber in eyes with macular edema. This was a multicenter, retrospective, observational chart review of data that included patients with macular edema who had been treated with at least one intravitreal dexamethasone injection. Patients with incomplete chart information during the follow-up period were excluded. The prevalence of implant migration in 468 patients, considering the number of injections, was 1.6%, with significant associations between implant migration and cataract surgery (P = 0.043) and intraocular lens status (P = 0.005) and a trend toward statistical significance (P = 0.057) with vitrectomy. A higher rate of implant migration into the anterior chamber was observed in vitrectomized eyes (4.8%) when compared with patients who did not undergo a vitrectomy (1.6%). The implants that migrated were removed with forceps with/without viscoelastic expression or with 20-gauge cannulas connected to the vitreous cutter machine. The risk of implant migration into the anterior chamber was 1.6%. Risk factors were a history of cataract surgery or vitrectomy and aphakia. When anterior migration occurs, rapid removal ...Continue Reading

References

Jan 12, 2011·Archives of Ophthalmology·Careen LowderUNKNOWN Ozurdex HURON Study Group
Apr 14, 2011·Retina·David S BoyerUNKNOWN Ozurdex CHAMPLAIN Study Group
Apr 16, 2011·Advances in Therapy·Nikolas J S LondonJulia A Haller
Aug 24, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Diamar Pardo-LópezManuel Díaz-Llopis
Oct 1, 2011·Journal of Ophthalmic Inflammation and Infection·Reema BansalAmod Gupta
Jan 18, 2013·Ocular Immunology and Inflammation·Sarita A Kishore, Shlomit Schaal
Jul 1, 2012·Retinal Cases & Brief Reports·James A EadieAntonio Capone
Dec 3, 2014·Survey of Ophthalmology·Suqin GuoMarco Zarbin
Aug 8, 2015·Ophthalmic Surgery, Lasers & Imaging Retina·Christopher R SteltonSteven Yeh
Sep 26, 2015·Retina·Ehsan RahimyJulia A Haller
Apr 29, 2016·Retinal Cases & Brief Reports·Diego Ruiz-CasasAlfonso Casado
Jun 12, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hyunseung KangMin Kim
Dec 21, 2017·American Journal of Ophthalmology Case Reports·Haifa A MadiSaurabh Ghosh

❮ Previous
Next ❯

Citations

Jan 17, 2020·Taiwan Journal of Ophthalmology·Jorge Chawan-SaadLihteh Wu
Mar 31, 2021·European Journal of Ophthalmology·Sarah M ChangLisa S Schocket

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.